Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate

Base Information

Chemical Name:Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate
CAS No.:457947-61-4
Molecular Formula:C9H9ClN2O5
Molecular Weight:260.634
Hs Code.:
DSSTox Substance ID:DTXSID80477514
Wikidata:Q82310269

Synonyms:Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate;457947-61-4;4-Amino-5-chloro-2-methoxy-3-nitro-benzoic Acid Methyl Ester;SCHEMBL1115896;DTXSID80477514;IHQKJDKMQBJBML-UHFFFAOYSA-N;AKOS027447908;BS-51510;E76792

Suppliers and Price of Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:260.0199991
Heavy Atom Count:17
Complexity:308

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1C(=O)OC)Cl)N)[N+](=O)[O-]

Technology Process of Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate

There total 3 articles about Methyl 4-amino-5-chloro-2-methoxy-3-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 126463-85-2
4-acetylamino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

: 457947-61-4
4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

Guidance literature:: 4-acetylamino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester; With sulfuric acid; In methanol; for 7h; Reflux;

With sodium hydrogencarbonate; In water;

Reference yield:

: 4093-31-6
methyl 2-methoxy 4-acetamido 5-chloro benzoate

: 457947-61-4
4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / HNO₃ / 0.17 h / 20 °C

2: 94 percent / aq. H₂SO₄ / methanol / 9 h / Heating

With sulfuric acid; nitric acid; In methanol;
DOI:10.1021/ja0300158

Reference yield:

: 20896-27-9
methyl 4-amino-5-chloro-2-methoxybenzoate

: 457947-61-4
4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 12 h / Reflux

2: nitric acid / 0.33 h / 20 °C

3: sulfuric acid / methanol / Reflux

With sulfuric acid; nitric acid; In methanol;