Azanator

Base Information

Chemical Name:Azanator
CAS No.:37855-92-8
Molecular Formula:C18H18N2O
Molecular Weight:278.354
Hs Code.:2934999090
European Community (EC) Number:253-694-4
UNII:699725286I
DSSTox Substance ID:DTXSID50191295
Nikkaji Number:J19.266J
Wikidata:Q27264332
NCI Thesaurus Code:C72711
ChEMBL ID:CHEMBL2110934
Mol file:37855-92-8.mol

Synonyms:5-(4-(N-methyl)piperidylidene)-5H-(1)benzopyrano(2,3-b)pyridine;azanator;Sch 15280;Sch-15280

Suppliers and Price of Azanator

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
AzanatorMaleate
25 mg
$ 1500.00

Medical Isotopes, Inc.
AzanatorMaleate
5 mg
$ 950.00

American Custom Chemicals Corporation
AZANATOR 95.00%
5MG
$ 502.23

Total 3 raw suppliers

Chemical Property of Azanator

Chemical Property:

Vapor Pressure:1.11E-07mmHg at 25°C
Melting Point:125-127 °C
Boiling Point:432.4°Cat760mmHg
PKA:8.58±0.20(Predicted)
Flash Point:215.3°C
PSA：25.36000
Density:1.206g/cm³
LogP:3.65270
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:278.141913202
Heavy Atom Count:21
Complexity:409

Purity/Quality:

99% ^*data from raw suppliers

AzanatorMaleate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC(=C2C3=C(N=CC=C3)OC4=CC=CC=C42)CC1
Uses Bronchodilator.

Technology Process of Azanator

There total 4 articles about Azanator which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 37855-82-6
5-(1-methyl-piperidin-4-yl)-5H-chromeno[2,3-b]pyridin-5-ol

: 37855-92-8
5-(1-methyl-piperidin-4-ylidene)-5H-chromeno[2,3-b]pyridine

Guidance literature:: With PPA; at 100 - 120 ℃;
DOI:10.1021/jm00235a001

Reference yield:

: 35620-71-4
2-phenoxypyridine-3-carboxylic acid

: 37855-92-8
5-(1-methyl-piperidin-4-ylidene)-5H-chromeno[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: polyphosphoric acid / 16 h / 100 - 120 °C

2: (i) NaNH₂, THF, (ii) /BRN= 103023/

3: polyphosphoric acid / 100 - 120 °C

With PPA;
DOI:10.1021/jm00235a001

Reference yield:

: 6537-46-8
5H-benzopyrano[2,3-b]pyridin-5-one

: 37855-92-8
5-(1-methyl-piperidin-4-ylidene)-5H-chromeno[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NaNH₂, THF, (ii) /BRN= 103023/

2: polyphosphoric acid / 100 - 120 °C

With PPA;
DOI:10.1021/jm00235a001