Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-

Base Information

Chemical Name:Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-
CAS No.:458563-75-2
Molecular Formula:C₂₁H₃₅N₃O₃
Molecular Weight:377.527
Hs Code.:2934999090

Synonyms:Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-;(4S,4'S,4''S)-2,2',2''-(2-Methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)oxazole];

Suppliers and Price of Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
1,2,2-Tris[(S)-4-isopropyl-4,5-dihydro-2-oxazolyl]propane
1 g
$ 2016.00

Crysdot
1,2,2-Tris[(S)-4-isopropyl-4,5-dihydro-2-oxazolyl]propane 95+%
5g
$ 746.00

AK Scientific
1,2,2-Tris[(S)-4-isopropyl-4,5-dihydro-2-oxazolyl]propane
1g
$ 1275.00

AK Scientific
1,2,2-Tris[(S)-4-isopropyl-4,5-dihydro-2-oxazolyl]propane
250mg
$ 532.00

Total 3 raw suppliers

Chemical Property of Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-

Chemical Property:

Boiling Point:453.1±40.0 °C(Predicted)
PSA：64.77000
Density:1.18±0.1 g/cm3(Predicted)
LogP:2.04950

Purity/Quality:

97% ^*data from raw suppliers

1,2,2-Tris[(S)-4-isopropyl-4,5-dihydro-2-oxazolyl]propane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)-

There total 3 articles about Oxazole, 2,2',2''-(2-methyl-1-ethanyl-2-ylidene)tris[4,5-dihydro-4-(1-methylethyl)-, (4S,4'S,4''S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: (S)-N,N,N-tris[1-(hydroxymethyl)-2-methylpropyl]-1,2,3-propane tricarboxamide

: 458563-75-2
(S)-1,2,2-tris[2-[4-isopropyl-1,3-oxazolinyl]] propane

Guidance literature:: With triethylamine; triphenylphosphine; In tetrachloromethane; acetonitrile; at 25 ℃;
DOI:10.1021/jo035552p

Reference yield:

: 221196-91-4
(S)-2-(chloromethyl)-4-isopropyl-4,5-dihydrooxazole

: 499786-37-7
1,1‐bis[(4S)‐4‐isopropyl‐4,5‐dihydrooxazol‐2‐yl]ethane

: 458563-75-2
(S)-1,2,2-tris[2-[4-isopropyl-1,3-oxazolinyl]] propane

Guidance literature:: 1,1‐bis[(4S)‐4‐isopropyl‐4,5‐dihydrooxazol‐2‐yl]ethane; With tert.-butyl lithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

(S)-2-(chloromethyl)-4-isopropyl-4,5-dihydrooxazole; In tetrahydrofuran; hexane; at -78 - 20 ℃;
DOI:10.1021/jo050595m

Reference yield:

: 2026-48-4,473-75-6
(S)-valinol

: 458563-75-2
(S)-1,2,2-tris[2-[4-isopropyl-1,3-oxazolinyl]] propane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 83 percent / triethylamine / CH₂Cl₂ / 0 - 20 °C

2.1: tert-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

2.2: tetrahydrofuran; hexane / -78 - 20 °C

With tert.-butyl lithium; triethylamine; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/jo050595m