4-Pyridinecarboxylic acid, 2-ethyl-, hydrazide

Base Information

• Chemical Name: 4-Pyridinecarboxylic acid, 2-ethyl-, hydrazide
• CAS No.: 4608-25-7
• Molecular Formula: C8H11N3O
• Molecular Weight: 165.195
• Mol file: 4608-25-7.mol

Synonyms:

Chemical Property of 4-Pyridinecarboxylic acid, 2-ethyl-, hydrazide

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Pyridinecarboxylic acid, 2-ethyl-, hydrazide

There total 1 articles about 4-Pyridinecarboxylic acid, 2-ethyl-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-ethyl-6-hydroxy-isonicotinic acid (54881-17-3) → 2-ethyl-isonicotinic acid hydrazide (4608-25-7)

Guidance literature:

Multi-step reaction with 3 steps

1: POCl₃; PCl₅ / 140 °C / Behandeln des Reaktionsprodukts mit Aethanol

2: palladium/charcoal; ethanol; potassium acetate / Hydrogenation

3: ethanol; aqueous N₂H₄+H₂O

With palladium on activated charcoal; ethanol; phosphorus pentachloride; potassium acetate; hydrazine hydrate; trichlorophosphate;

DOI:10.1002/hlca.19550380425

Reference yield:

2-ethyl-isonicotinic acid hydrazide (4608-25-7) + vanillin (121-33-5,8014-42-4) → 2-ethyl-isonicotinic acid vanillylidenehydrazide

Guidance literature:

With water;

DOI:10.1002/hlca.19550380425

upstream raw materials:

2-ethyl-6-hydroxy-isonicotinic acid