6-METHYL-3,4-PYRIDINEDIMETHANOL

Base Information

• Chemical Name: 6-METHYL-3,4-PYRIDINEDIMETHANOL
• CAS No.: 4664-11-3
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.17800
• Hs Code.: 2933399090
• Mol file: 4664-11-3.mol

Synonyms:3-Deoxypyridoxine;2-Methyl-4,5-bis-hydroxymethyl-pyridin;3,4-Pyridinedimethanol,6-methyl;4,5-bis-hydroxymethyl-2-methyl-pyridine;3-Desoxy-pyridoxol;

Chemical Property of 6-METHYL-3,4-PYRIDINEDIMETHANOL

Chemical Property:

• PSA: 53.35000
• LogP: 0.37460

Purity/Quality:

95% ^*data from raw suppliers

6-methyl-3,4-Pyridinedimethanol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-METHYL-3,4-PYRIDINEDIMETHANOL

There total 10 articles about 6-METHYL-3,4-PYRIDINEDIMETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

dimethyl 6-methyl-3,4-pyridinedicarboxylate (56912-90-4) → 2-methyl-4,5-dihydroxymethylpyridine (4664-11-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 17h; Inert atmosphere;

DOI:10.1039/c5ra25779d

Reference yield:

6-methyl-pyridine-3,4-dicarboxylic acid diethyl ester → 2-methyl-4,5-dihydroxymethylpyridine (4664-11-3)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01145a040

Reference yield:

6-Methyl-pyridine-3,4-dicarboxylic acid (3307-80-0) → 2-methyl-4,5-dihydroxymethylpyridine (4664-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanolic HCl

2: lithium alanate; diethyl ether

With hydrogenchloride; lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/ja01145a040

upstream raw materials:

propargyl alcohol

acetonitrile

6-Methyl-pyridine-3,4-dicarboxylic acid

(4-ethoxymethyl-6-methyl-[3]pyridyl)-methanol

Refernces

• 1、 Fatland,Eaton. "Cobalt-catalyzed alkyne-nitrile cyclotrimerization to form pyridines in aqueous solution.". . p. 3131 - 3133. Retrieved 2007/10/03.