(2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one

Base Information

Chemical Name:(2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one
CAS No.:473812-31-6
Molecular Formula:C24H36O3
Molecular Weight:372.548
Hs Code.:
DSSTox Substance ID:DTXSID10453225
Nikkaji Number:J2.669.289J
Wikidata:Q82274323
Mol file:473812-31-6.mol

Synonyms:CTK1C7288;473812-31-6;DTXSID10453225;(5R)-5alpha-[(R)-1-(Benzyloxy)tridecyl]-2,5-dihydrofuran-2-one

Suppliers and Price of (2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of (2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one

Chemical Property:

XLogP3:7.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:15
Exact Mass:372.26644501
Heavy Atom Count:27
Complexity:412

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCC(C1C=CC(=O)O1)OCC2=CC=CC=C2
Isomeric SMILES:CCCCCCCCCCCC[C@H]([C@H]1C=CC(=O)O1)OCC2=CC=CC=C2

Technology Process of (2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one

There total 5 articles about (2R)-2-[(1R)-1-phenylmethoxytridecyl]-2H-furan-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 473812-21-4
(3R,4R)-4-(benzyloxy)hexadec-1-en-3-yl acrylate

: 473812-31-6
(5R)-5-[(R)-1-benzyloxytridecyl]-5H-furan-2-one

Guidance literature:: With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In toluene; for 4h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetasy.2008.11.004

Reference yield:

: 473812-14-5
(3R,4R)-4-(benzyloxy)hexadec-1-en-3-ol

: 473812-31-6
(5R)-5-[(R)-1-benzyloxytridecyl]-5H-furan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / triethylamine; DMAP / CH₂Cl₂ / 3 h / 0 °C

2: 80 percent / [Ru(P(Cy₃)(=CHPh)(C(NMes)2CH₂CH₂)Cl₂] / toluene / Heating

With dmap; triethylamine; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; toluene;
DOI:10.1002/1099-0690(200208)2002:15<2649::AID-EJOC2649>3.0.CO;2-T

Reference yield:

: 473812-07-6
(R)-2-benzyloxytetradecanal

: 473812-31-6
(5R)-5-[(R)-1-benzyloxytridecyl]-5H-furan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 3.32 g / MgBr₂*Et₂O / CH₂Cl₂ / -78 °C

2: 70 percent / triethylamine; DMAP / CH₂Cl₂ / 3 h / 0 °C

3: 80 percent / [Ru(P(Cy₃)(=CHPh)(C(NMes)2CH₂CH₂)Cl₂] / toluene / Heating

With dmap; triethylamine; magnesium bromide; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; toluene;
DOI:10.1002/1099-0690(200208)2002:15<2649::AID-EJOC2649>3.0.CO;2-T