Antide

Base Information

• Chemical Name: Antide
• CAS No.: 112568-12-4
• Molecular Formula: C82H108ClN17O14
• Molecular Weight: 1591.32
• Hs Code.: 3504009000
• Mol file: 112568-12-4.mol

Synonyms:(N-Acetyl-3-(naphhalen-2-yl)-D-alanyl)-p-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-N(sup 6)-nicotinyl-L-lysyl-N(sup 6)-nicotinyl-D-lysyl-L-leucyl-N(sup6)-isopropyl-L-lysyl-L-prolyl-D-alaninamide;BRN 4866881;ORF 23541;D 21074;Iturelix;ORF 23541;Orf-32541;

Chemical Property of Antide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.592
• Boiling Point: 1798 °C at 760 mmHg
• PKA: 12.78±0.46(Predicted)
• Flash Point: 1041.2 °C
• PSA: 454.43000
• Density: 1.258 g/cm³
• LogP: 8.32170
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Antide Acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 60
• Safety Statements: 53-22-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Reversible inhibition of gonadotropin secretion and subsequent suppression of ovarian and testicular steroid secretio (gonadotropin releasing hormone antagonist). Antide, is a GnRH and LH-RH antagonist, and with high anti-ovulatory and negligible histamine release activity.

Technology Process of Antide

There total 1 articles about Antide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-DPal (98266-33-2,105454-25-9) + N-Boc-D-(4-Cl)Phe-OH (57292-44-1) + Boc-D-2Nal-OH (76985-10-9) + (S)-3-(benzoyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid (78545-07-0) → antide (112568-12-4)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm00101a003

upstream raw materials:

Boc-DPal

N-Boc-D-(4-Cl)Phe-OH

Boc-D-2Nal-OH

(S)-3-(benzoyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid

Refernces