Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl-

Base Information

• Chemical Name: Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl-
• CAS No.: 4771-35-1
• Molecular Formula: C₁₀H₇BrClNS
• Molecular Weight: 288.595
• DSSTox Substance ID: DTXSID70480496
• Wikidata: Q82315294
• Mol file: 4771-35-1.mol

Synonyms:4771-35-1;Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl-;SCHEMBL11376938;DTXSID70480496

Chemical Property of Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl-

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 286.91711
• Heavy Atom Count: 14
• Complexity: 187

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NC(=C(S2)Br)CCl

Technology Process of Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl-

There total 1 articles about Thiazole, 5-bromo-4-(chloromethyl)-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-bromo-4-chloromethyl-2-phenyl-thiazole (4771-35-1)

Guidance literature:

2-Phenyl-4-chlormethyl-5-carboxythiazol, Br2;

DOI:10.1002/ardp.19763090207

Reference yield:

5-bromo-4-chloromethyl-2-phenyl-thiazole (4771-35-1) → 5-bromo-2-phenylthiazole-4-carbaldehyde (20949-91-1)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O

2: Na₂Cr₂O₇*2H₂O / acetic acid

With sodium dichromate; water; In acetic acid;

DOI:10.1002/ardp.19743070202

Reference yield:

5-bromo-4-chloromethyl-2-phenyl-thiazole (4771-35-1) → (5-bromo-2-phenyl-thiazol-4-yl)-methanol (21160-54-3)

Guidance literature:

With water;

DOI:10.1002/ardp.19743070202

Downstream raw materials:

5-bromo-4-chloromethyl-2-(4-nitro-phenyl)-thiazole

(5-bromo-2-phenyl-thiazol-4-yl)-methanol

2-bromo-10-(5-bromo-2-phenyl-thiazol-4-ylmethyl)-10H-acridin-9-one

2,7-dibromo-10-(5-bromo-2-phenyl-thiazol-4-ylmethyl)-10H-acridin-9-one