(3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol

Base Information

Chemical Name:(3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol
CAS No.:145627-69-6
Molecular Formula:
Molecular Weight:266.3343
Hs Code.:
DSSTox Substance ID:DTXSID401030676
Nikkaji Number:J518.867I
Mol file:145627-69-6.mol

Synonyms:145627-69-6;DTXSID401030676;(3alpha,4beta)-11-Methylgona-1,5(10),6,8,11,13-hexaene-3,4-diol

Suppliers and Price of (3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:500.585°C at 760 mmHg
Flash Point:242.175°C
Density:1.312g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:266.130679813
Heavy Atom Count:20
Complexity:404

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(CCC2)C3=C1C4=C(C=C3)C(C(C=C4)O)O
Isomeric SMILES:CC1=CC2=C(CCC2)C3=C1C4=C(C=C3)[C@H]([C@@H](C=C4)O)O

Technology Process of (3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol

There total 3 articles about (3R,4R)-11-methyl-4,15,16,17-tetrahydro-3H-cyclopenta[a]phenanthrene-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 145627-80-1
15,16-Dihydro-11-methylcyclopenta phenanthrene-3,4-dione

: 145627-69-6
trans-3,4-Dihydroxy-11-methyl-3,4,15,16-tetrahydrocyclopenta phenanthrene

Guidance literature:: With sodium tetrahydroborate; oxygen; In ethanol; for 96h;
DOI:10.1021/jo00054a017

Reference yield:

: 145627-78-7
15,16-Dihydro-3-hydroxy-11-methylcyclopenta phenanthrene

: 145627-69-6
trans-3,4-Dihydroxy-11-methyl-3,4,15,16-tetrahydrocyclopenta phenanthrene

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / (SO₃K)2NO, KH₂PO₄, Adogen 464 / benzene; H₂O / 4 h

2: 71 percent / NaBH₄, O₂ / ethanol / 96 h

With sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassium nitrososulfonate; oxygen; In ethanol; water; benzene;
DOI:10.1021/jo00054a017

Reference yield:

: 145627-72-1
15,16-Dihydro-3-methoxy-11-methylcyclopenta phenanthrene

: 145627-69-6
trans-3,4-Dihydroxy-11-methyl-3,4,15,16-tetrahydrocyclopenta phenanthrene

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / NaSEt / dimethylformamide / Heating

2: 84 percent / (SO₃K)2NO, KH₂PO₄, Adogen 464 / benzene; H₂O / 4 h

3: 71 percent / NaBH₄, O₂ / ethanol / 96 h

With sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassium nitrososulfonate; oxygen; sodium thioethylate; In ethanol; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo00054a017