Technology Process of 2,6,10-Dodecatrienoic acid, 3,7,11-trimethyl-, pentafluorophenyl ester,
(2E,6E)-
There total 5 articles about 2,6,10-Dodecatrienoic acid, 3,7,11-trimethyl-, pentafluorophenyl ester,
(2E,6E)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dicyclohexyl-carbodiimide;
In
ethyl acetate;
for 24h;
DOI:10.1021/jo026295b
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 51 percent / NaH; n-BuLi / tetrahydrofuran; hexane / 0.5 h / 0 - 20 °C
2: 79 percent / LiHMDS / tetrahydrofuran; diethyl ether / 3.5 h / 20 °C
3: 93 percent / CuI; MeLi / tetrahydrofuran; diethyl ether / 3 h / -30 °C
4: 78 percent / aq. NaOH; NaHCO3 / tetrahydrofuran
5: 99 percent / DCC / ethyl acetate / 24 h
With
sodium hydroxide; copper(l) iodide; n-butyllithium; methyllithium; sodium hydride; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; lithium hexamethyldisilazane;
In
tetrahydrofuran; diethyl ether; hexane; ethyl acetate;
DOI:10.1021/jo026295b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 78 percent / aq. NaOH; NaHCO3 / tetrahydrofuran
2: 99 percent / DCC / ethyl acetate / 24 h
With
sodium hydroxide; sodium hydrogencarbonate; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; ethyl acetate;
DOI:10.1021/jo026295b
