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Technology Process of PHA-543613 Dihydrochloride

PHA-543613 Dihydrochloride

Base Information
  • Chemical Name:PHA-543613 Dihydrochloride
  • CAS No.:478148-58-2
  • Molecular Formula:C15H17N3O2.2ClH
  • Molecular Weight:344.23600
  • Hs Code.:
  • UNII:Z7950E6X01
  • Mol file:478148-58-2.mol
PHA-543613 Dihydrochloride

Synonyms:PHA-543613 Dihydrochloride;478148-58-2;PHA 543613 dihydrochloride;PHA-543613 dihydrochloride salt;PHA-543613E;UNII-Z7950E6X01;Z7950E6X01;PHA-543613 (dihydrochloride);Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, dihydrochloride;Furo(2,3-C)pyridine-5-carboxamide, N-(3R)-1-azabicyclo(2.2.2)oct-3-yl-, hydrochloride (1:2);N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide;dihydrochloride;SCHEMBL6007449;HY-105670B;CS-0134433;E99019;(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride

Suppliers and Price of PHA-543613 Dihydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • PHA-543613 Dihydrochloride
  • 10mg
  • $ 460.00
Total 3 raw suppliers
Chemical Property of PHA-543613 Dihydrochloride
Chemical Property:
  • Melting Point:>300?C 
  • PSA：58.37000 
  • LogP:3.58460 
  • Storage Temp.:Refrigerator 
  • Solubility.:DMSO, Methanol 
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:2
  • Exact Mass:343.0854322
  • Heavy Atom Count:22
  • Complexity:381
Purity/Quality:

97% *data from raw suppliers

PHA-543613 Dihydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CN2CCC1C(C2)NC(=O)C3=NC=C4C(=C3)C=CO4.Cl.Cl
  • Isomeric SMILES:C1CN2CCC1[C@H](C2)NC(=O)C3=NC=C4C(=C3)C=CO4.Cl.Cl
  • Uses PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays. PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential ther
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