2-Bromo-1,6,7-trimethoxy-3-methylnaphthalene

Base Information

• Chemical Name: 2-Bromo-1,6,7-trimethoxy-3-methylnaphthalene
• CAS No.: 7143-05-7
• Molecular Formula: C14H15BrO3
• Molecular Weight: 311.1711
• NSC Number: 40280
• DSSTox Substance ID: DTXSID30285040
• Wikidata: Q82020265
• ChEMBL ID: CHEMBL1879286
• Mol file: 7143-05-7.mol

Synonyms:MLS002608205;7143-05-7;2-bromo-1,6,7-trimethoxy-3-methylnaphthalene;NSC40280;CHEMBL1879286;DTXSID30285040;HMS3078A14;NSC-40280;SMR001526956;1,6,7-trimethoxy-2-bromo-3-methylnaphthalene

Chemical Property of 2-Bromo-1,6,7-trimethoxy-3-methylnaphthalene

Chemical Property:

• Vapor Pressure: 3.01E-06mmHg at 25°C
• Boiling Point: 400.1°Cat760mmHg
• Flash Point: 164.9°C
• Density: 1.364g/cm³
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 310.02046
• Heavy Atom Count: 18
• Complexity: 274

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=CC(=C(C=C2C(=C1Br)OC)OC)OC

Technology Process of 2-Bromo-1,6,7-trimethoxy-3-methylnaphthalene

There total 2 articles about 2-Bromo-1,6,7-trimethoxy-3-methylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,7-dimethoxy-3-methyl-3,4-dihydro-2H-naphthalen-1-one (408312-82-3) → 2-bromo-1,6,7-trimethoxy-3-methyl-naphthalene (7143-05-7)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine

2: methanol. sodium methylate

With bromine; sodium methylate;

DOI:10.1021/ja01562a046

Reference yield:

2,2-dibromo-6,7-dimethoxy-3-methyl-3,4-dihydro-2H-naphthalen-1-one (100380-61-8) + dimethyl sulfate (77-78-1) → 2-bromo-1,6,7-trimethoxy-3-methyl-naphthalene (7143-05-7)

Guidance literature:

With sodium methylate;

DOI:10.1021/ja01562a046

upstream raw materials:

2,2-dibromo-6,7-dimethoxy-3-methyl-3,4-dihydro-2H-naphthalen-1-one

dimethyl sulfate

6,7-dimethoxy-3-methyl-3,4-dihydro-2H-naphthalen-1-one