Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester

Base Information

Chemical Name:Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester
CAS No.:478314-26-0
Molecular Formula:C₂₃H₄₂O₅
Molecular Weight:398.583
Hs Code.:

Propanoic acid, 2,2-dimethyl-,
(2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl
-2-(3-methyl-2-butenyl)cyclohexyl]propyl ester

Synonyms:

Suppliers and Price of Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester

There total 9 articles about Propanoic acid, 2,2-dimethyl-, (2S)-2-[(1R,2S,3S,4R)-2-(hydroxymethyl)-3-(methoxymethoxy)-4-methyl -2-(3-methyl-2-butenyl)cyclohexyl]propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2,2-Dimethyl-propionic acid (S)-2-[(1R,2S,3S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-3-methoxymethoxy-4-methyl-2-(3-methyl-but-2-enyl)-cyclohexyl]-propyl ester

: 478314-26-0
2,2-Dimethyl-propionic acid (S)-2-[(1R,2S,3S,4R)-2-hydroxymethyl-3-methoxymethoxy-4-methyl-2-(3-methyl-but-2-enyl)-cyclohexyl]-propyl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 50 ℃;
DOI:10.1016/S0040-4039(02)01831-2

Reference yield:

: 2244-16-8,6485-40-1
(S)-p-mentha-6,8-dien-2-one

: 478314-26-0
2,2-Dimethyl-propionic acid (S)-2-[(1R,2S,3S,4R)-2-hydroxymethyl-3-methoxymethoxy-4-methyl-2-(3-methyl-but-2-enyl)-cyclohexyl]-propyl ester

Guidance literature:: Multi-step reaction with 8 steps

1.1: LDA / tetrahydrofuran / -42 °C

1.2: -42 - 20 °C

2.1: LDA / tetrahydrofuran / -78 °C

2.2: -78 °C

3.1: 70 percent / Na; liq. NH₃ / ethanol / -78 °C

4.1: imidazole / dimethylformamide / 20 °C

5.1: iPr₂NEt / 1,2-dichloro-ethane / 50 °C

6.1: 9-BBN / tetrahydrofuran / 20 °C

6.2: 92 percent / NaOH; H₂O₂

7.1: pyridine / 0 °C

8.1: TBAF / tetrahydrofuran / 50 °C

With pyridine; 1H-imidazole; 9-borabicyclo[3.3.1]nonane dimer; tetrabutyl ammonium fluoride; ammonia; sodium; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(02)01831-2

Reference yield:

: 870-63-3
prenyl bromide

: 478314-26-0
2,2-Dimethyl-propionic acid (S)-2-[(1R,2S,3S,4R)-2-hydroxymethyl-3-methoxymethoxy-4-methyl-2-(3-methyl-but-2-enyl)-cyclohexyl]-propyl ester

Guidance literature:: Multi-step reaction with 8 steps

1.1: LDA / tetrahydrofuran / -42 °C

1.2: -42 - 20 °C

2.1: LDA / tetrahydrofuran / -78 °C

2.2: -78 °C

3.1: 70 percent / Na; liq. NH₃ / ethanol / -78 °C

4.1: imidazole / dimethylformamide / 20 °C

5.1: iPr₂NEt / 1,2-dichloro-ethane / 50 °C

6.1: 9-BBN / tetrahydrofuran / 20 °C

6.2: 92 percent / NaOH; H₂O₂

7.1: pyridine / 0 °C

8.1: TBAF / tetrahydrofuran / 50 °C

With pyridine; 1H-imidazole; 9-borabicyclo[3.3.1]nonane dimer; tetrabutyl ammonium fluoride; ammonia; sodium; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(02)01831-2