6-Chloroquinoline-4-carbaldehyde

Base Information

Chemical Name:6-Chloroquinoline-4-carbaldehyde
CAS No.:482583-75-5
Molecular Formula:C₁₀H₆ClNO
Molecular Weight:191.617
Hs Code.:
DSSTox Substance ID:DTXSID40389821
Wikidata:Q82186003

Synonyms:6-chloroquinoline-4-carbaldehyde;482583-75-5;6-Chloro-quinoline-4-carbaldehyde;SCHEMBL3252945;6-chloroquinoline 4-carbaldehyde;DTXSID40389821;CBKMCVSSHQYURY-UHFFFAOYSA-N;AKOS000588926;SB67738;6-chloroquinoline-4-carbaldehyde, AldrichCPR;CS-0140345;EN300-237976;F2102-0012;Z166630818

Suppliers and Price of 6-Chloroquinoline-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Chloroquinoline-4-carbaldehyde 97%
5g
$ 495.00

Crysdot
6-Chloroquinoline-4-carbaldehyde 97%
10g
$ 867.00

Chemenu
6-Chloroquinoline-4-carbaldehyde 97%
10g
$ 818.00

Chemenu
6-Chloroquinoline-4-carbaldehyde 97%
5g
$ 468.00

Total 5 raw suppliers

Chemical Property of 6-Chloroquinoline-4-carbaldehyde

Chemical Property:

PSA：29.96000
LogP:2.70070
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:191.0137915
Heavy Atom Count:13
Complexity:197

Purity/Quality:

97% ^*data from raw suppliers

6-Chloroquinoline-4-carbaldehyde 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=CC(=C2C=C1Cl)C=O
Uses 6-Chloroquinoline-4-carboxaldehyde is used as a reactant in the preparation of pyrazolopyrimidinediones as Helicobacter pylori glutamate racemase inhibitors and selective antibacterial agents.

Technology Process of 6-Chloroquinoline-4-carbaldehyde

There total 3 articles about 6-Chloroquinoline-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 41037-29-0
6-chloro-4-methylquinoline

: 482583-75-5
6-chloroquinoline-4-carboxaldehyde

Guidance literature:: With dichloro-acetic acid; [bis(acetoxy)iodo]benzene; water; In dimethyl sulfoxide; at 20 ℃; for 48h; chemoselective reaction; Sealed tube;
DOI:10.1002/asia.202100704

Reference yield:

: 4203-18-3
4,6-dichloroquinoline

: 482583-75-5
6-chloroquinoline-4-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: manganese(ll) chloride / tetrahydrofuran / 3 h / 0 °C / Inert atmosphere

2: [bis(acetoxy)iodo]benzene; dichloro-acetic acid; water / dimethyl sulfoxide / 48 h / 20 °C / Sealed tube

With dichloro-acetic acid; [bis(acetoxy)iodo]benzene; water; manganese(ll) chloride; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1002/asia.202100704