4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide

Base Information

Chemical Name:4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide
CAS No.:4826-22-6
Molecular Formula:C10H10N2O4S
Molecular Weight:254.26200
Hs Code.:
DSSTox Substance ID:DTXSID50875886
Nikkaji Number:J347.877G
Wikidata:Q82857369
Mol file:4826-22-6.mol

Synonyms:4826-22-6;4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide;3-(1,1-dioxido-2H-benzo[e][1,2,4]thiadiazin-3-yl)propanoic acid;starbld0010477;DTXSID50875886;AKOS015831012;EU-0060957;F0918-6796;PROPANOIC ACID, 3-(4H-1,2,4-BENZOTHIADIAZIN-3-YL

Suppliers and Price of 4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide

Chemical Property:

Melting Point:215 - 217 °C (petroleum ether)
PSA：104.21000
LogP:1.71850
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:254.03612798
Heavy Atom Count:17
Complexity:438

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=NS2(=O)=O)CCC(=O)O

Technology Process of 4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide

There total 6 articles about 4H-1,2,4-Benzothiadiazine-3-propanoic acid 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4826-19-1
N-<2'-(Aminosulfonyl)phenyl>-2,5-pyrrolidinedione

: 4826-22-6
1,2,4-Benzothiadiazin-1,1-dioxid-3-propionsaeure

Guidance literature:: With sodium hydroxide; for 0.166667h;
DOI:10.1002/ardp.19853181008

Reference yield: 86.0%

: 4-<<2-(Aminosulfonyl)phenyl>amino>-4-oxo-butanoic acid methyl ester

: 4826-22-6
1,2,4-Benzothiadiazin-1,1-dioxid-3-propionsaeure

Guidance literature:: With sodium hydroxide; for 0.166667h;
DOI:10.1002/ardp.19853181008

Reference yield:

: 3306-62-5
2-AMINOBENZENESULFONAMIDE

: 4826-22-6
1,2,4-Benzothiadiazin-1,1-dioxid-3-propionsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-acetamide / 20 - 25 °C

2: 100 percent / 4percent aq. NaOH / 0.17 h

With sodium hydroxide; In N,N-dimethyl acetamide;
DOI:10.1002/ardp.19853181008