2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-

Base Information

Chemical Name:2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-
CAS No.:485322-68-7
Molecular Formula:C55H82O8Si
Molecular Weight:899.337
Hs Code.:

2(5H)-Furanone,
3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S,
6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec
yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-

Synonyms:

Suppliers and Price of 2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)-

There total 22 articles about 2(5H)-Furanone, 3-[(2R,10S)-2-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-10-hydroxy-10-[(2S, 6R)-tetrahydro-6-[(2R,5R)-tetrahydro-5-[(1R)-1-(methoxymethoxy)tridec yl]-2-furanyl]-2H-pyran-2-yl]-5-decen-7-ynyl]-5-methyl-, (5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 485322-57-4
3-[2-(tert-butyl-diphenyl-silanyloxy)-6-iodo-hex-5-enyl]-5-methyl-5H-furan-2-one

: 485322-56-3
(4S,5S,9R,10R,13R,14R)-1-(methoxymethoxy)-5,9:10,13-dioxido-1-hexacosyn-4-ol

: 485322-68-7
(S)-3-((E)-(2R,10S)-2-(tert-Butyl-diphenyl-silanyloxy)-10-hydroxy-10-{(2S,6R)-6-[(2R,5R)-5-((R)-1-methoxymethoxy-tridecyl)-tetrahydro-furan-2-yl]-tetrahydro-pyran-2-yl}-dec-5-en-7-ynyl)-5-methyl-5H-furan-2-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃;
DOI:10.1016/S0040-4039(02)02182-2

Reference yield:

: 485322-66-5
(2R,3S,7R,8R,11R,12R)-12-(methoxymethoxy)-3,7:8,11-dioxido-1,2-tetracosanediol

: 485322-68-7
(S)-3-((E)-(2R,10S)-2-(tert-Butyl-diphenyl-silanyloxy)-10-hydroxy-10-{(2S,6R)-6-[(2R,5R)-5-((R)-1-methoxymethoxy-tridecyl)-tetrahydro-furan-2-yl]-tetrahydro-pyran-2-yl}-dec-5-en-7-ynyl)-5-methyl-5H-furan-2-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: benzoyl chloride; pyridine / CH₂Cl₂ / 12 h / -20 - 5 °C

1.2: methanesulfonyl chloride; pyridine / CH₂Cl₂ / 7 h / -20 - 0 °C

1.3: 83 percent / NaOH / H₂O; tetrahydrofuran; methanol / 17 h / -20 - 5 °C

2.1: tetrahydrofuran; hexane / 1 h / -78 °C

2.2: 232 mg / BF₃*Et₂O / tetrahydrofuran / 2 h / -78 °C

3.1: 199 mg / K₂CO₃ / methanol / 5 h / 20 °C

4.1: 79 percent / Et₃N; CuI / (Ph₃P)2PdCl₂ / 2 h / 20 °C

With pyridine; copper(l) iodide; potassium carbonate; benzoyl chloride; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1016/S0040-4020(03)00135-2

Reference yield:

: 537666-02-7
(S)-1-{(2S,6R)-6-[(2R,5R)-5-((R)-1-Methoxymethoxy-tridecyl)-tetrahydro-furan-2-yl]-tetrahydro-pyran-2-yl}-4-trimethylsilanyl-but-3-yn-1-ol

: 485322-68-7
(S)-3-((E)-(2R,10S)-2-(tert-Butyl-diphenyl-silanyloxy)-10-hydroxy-10-{(2S,6R)-6-[(2R,5R)-5-((R)-1-methoxymethoxy-tridecyl)-tetrahydro-furan-2-yl]-tetrahydro-pyran-2-yl}-dec-5-en-7-ynyl)-5-methyl-5H-furan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 199 mg / K₂CO₃ / methanol / 5 h / 20 °C

2: 79 percent / Et₃N; CuI / (Ph₃P)2PdCl₂ / 2 h / 20 °C

With copper(l) iodide; potassium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In methanol;
DOI:10.1016/S0040-4020(03)00135-2