Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-

Base Information

Chemical Name:Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-
CAS No.:497058-33-0
Molecular Formula:C17H14O4
Molecular Weight:282.296
Hs Code.:
DSSTox Substance ID:DTXSID30357291
Nikkaji Number:J2.681.522C
Wikidata:Q82137155

Synonyms:497058-33-0;Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-;SCHEMBL5511361;DTXSID30357291

Suppliers and Price of Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:282.08920892
Heavy Atom Count:21
Complexity:370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C=C(O2)C(=O)C3=CC(=CC=C3)OC

Technology Process of Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)-

There total 4 articles about Methanone, (6-methoxy-2-benzofuranyl)(3-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1170149-78-6
(Z)-3-dimethylamino-2-(3-methoxyphenoxy)-1-(3-methoxyphenyl)prop-2-en-1-one

: 497058-33-0
(6-methoxybenzofuran-2-yl)(3-methoxyphenyl)methanone

Guidance literature:: With zinc(II) chloride; In dichloromethane; at 20 ℃; for 72h; Inert atmosphere;
DOI:10.1071/CH08243

Reference yield: 52.0%

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 5000-65-7
2-bromo-3'-methoxyacetophenone

: 497058-33-0
(6-methoxybenzofuran-2-yl)(3-methoxyphenyl)methanone

Guidance literature:: With potassium carbonate; at 100 ℃; for 24h;
DOI:10.1016/j.bioorg.2019.103459

Reference yield:

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 497058-33-0
(6-methoxybenzofuran-2-yl)(3-methoxyphenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) bromide / dichloromethane; ethyl acetate / 24 h / 85 °C

2: potassium carbonate / 24 h / 100 °C

With potassium carbonate; copper(ll) bromide; In dichloromethane; ethyl acetate;
DOI:10.1016/j.bioorg.2019.103459