5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde

Base Information

Chemical Name:5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde
CAS No.:500369-36-8
Molecular Formula:C₁₃H₁₀FNO₂
Molecular Weight:231.226
Hs Code.:
DSSTox Substance ID:DTXSID20595988
Wikidata:Q82491109
Mol file:500369-36-8.mol

Synonyms:5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde;500369-36-8;SCHEMBL755968;DTXSID20595988;BVVGWFSPUMXFQV-UHFFFAOYSA-N;AKOS018352710;5-(4-fluorobenzyloxy)-pyridine-2-carboaldehyde

Suppliers and Price of 5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:231.06955672
Heavy Atom Count:17
Complexity:242

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1COC2=CN=C(C=C2)C=O)F

Technology Process of 5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde

There total 1 articles about 5-[(4-Fluorophenyl)methoxy]pyridine-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 500369-36-8
5-(4-fluorobenzyloxy)-pyridine-2-carbaldehyde

Guidance literature:

Reference yield:

: 500369-36-8
5-(4-fluorobenzyloxy)-pyridine-2-carbaldehyde

: 579491-68-2
5-(4-fluoro-benzyloxy)-pyridine-2-carboxylic acid

Guidance literature:

Reference yield:

: 500369-36-8
5-(4-fluorobenzyloxy)-pyridine-2-carbaldehyde

: 3-[5-(4-fluorobenzyloxy)-pyridin-2-yl]-2-hydroxy-acrylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium bis(trimethylsilyl)amide / tetrahydrofuran / 0.5 h / -78 °C

1.2: tetrahydrofuran / 0.75 h / -78 - 0 °C

2.1: 32 percent / MeONa / methanol / 1 h / 20 °C

With sodium methylate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmc.2006.08.044