Norsolorinic acid

Base Information

• Chemical Name: Norsolorinic acid
• CAS No.: 10254-99-6
• Molecular Formula: C20H18 O7
• Molecular Weight: 370.359
• Hs Code.: 2914690090
• NSC Number: 138557
• UNII: Q1W7A6D0J6
• DSSTox Substance ID: DTXSID00145263
• Nikkaji Number: J55.278J
• Wikidata: Q27139538
• Metabolomics Workbench ID: 65614
• Mol file: 10254-99-6.mol

Synonyms:norsolorinic acid

Chemical Property of Norsolorinic acid

Chemical Property:

• Vapor Pressure: 2.82E-14mmHg at 25°C
• Boiling Point: 584.9°Cat760mmHg
• Flash Point: 321.5°C
• PSA: 132.13000
• Density: 1.479g/cm³
• LogP: 3.04740
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 370.10525291
• Heavy Atom Count: 27
• Complexity: 603

Purity/Quality:

98%,99%, ^*data from raw suppliers

NORSOLORINIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(=O)C1=C(C=C2C(=C1O)C(=O)C3=C(C2=O)C=C(C=C3O)O)O

Technology Process of Norsolorinic acid

There total 3 articles about Norsolorinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,1,3-tris(trimethylsiloxy)-1,3-butadiene (161787-95-7) + 3-chloro-6-hexanoyl-7-hydroxyjuglone (161788-11-0) → norsolorinic acid (10254-99-6)

Guidance literature:

With hydrogenchloride; 1.) -10 deg C, 30 min then r.t., 1 h; 2.) THF, r.t., 1 h;

DOI:10.1055/s-1994-25553

Reference yield: 46.0%

Brassard's diene (90857-62-8,106875-55-2,74272-66-5) + 3-chloro-6-hexanoyl-7-hydroxyjuglone (161788-11-0) → norsolorinic acid (10254-99-6) + solorinic acid (10210-21-6)

Guidance literature:

With hydrogenchloride; 1.) -10 deg C, 30 min then r.t., 1 h; 2.) THF, r.t., 1 h;

DOI:10.1055/s-1994-25553

Reference yield:

→ norsolorinic acid (10254-99-6)

Guidance literature:

upstream raw materials:

Brassard's diene

3-chloro-6-hexanoyl-7-hydroxyjuglone

1,1,3-tris(trimethylsiloxy)-1,3-butadiene

Downstream raw materials:

aflatoxin B₁

Refernces