Technology Process of N-[2-(6-chloro-5-methoxy-1-benzothiophen-3-yl)ethyl]acetamide
There total 19 articles about N-[2-(6-chloro-5-methoxy-1-benzothiophen-3-yl)ethyl]acetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 97 percent / acetic acid; acetic anhydride / 4 h / Ambient temperature
2: 96 percent / lithium aluminum hydride / diethyl ether / 2 h / Heating
3: 100 percent / diethyl ether; pyridine / 2 h / Heating
4: PPA, phosphorus pentoxide / toluene / 24 h / Heating
5: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight
6: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating
7: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature
With
phosphorus pentaoxide; lithium aluminium tetrahydride; dimethylsulfide; borane; ammonia; sodium acetate;
In
tetrahydrofuran; pyridine; diethyl ether; ethanol; water; acetic anhydride; ethylene glycol; acetic acid; toluene;
DOI:10.1002/jhet.5570200651
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / diethyl ether; pyridine / 2 h / Heating
2: PPA, phosphorus pentoxide / toluene / 24 h / Heating
3: 85 percent / ammonia / ethane-1,2-diol; ethanol / Ambient temperature; overnight
4: 81 percent / borane/dimethyl sulfide / tetrahydrofuran / 4 h / Heating
5: 82 percent / sodium acetate / H2O / 1 h / Ambient temperature
With
phosphorus pentaoxide; dimethylsulfide; borane; ammonia; sodium acetate;
In
tetrahydrofuran; pyridine; diethyl ether; ethanol; water; ethylene glycol; toluene;
DOI:10.1002/jhet.5570200651
