Varacin

Base Information

Chemical Name:Varacin
CAS No.:134029-48-4
Molecular Formula:C₁₀H₁₃NO₂S₅
Molecular Weight:339.549
Hs Code.:
UNII:85V98E6A3M
DSSTox Substance ID:DTXSID10158465
Nikkaji Number:J554.802K
Wikipedia:Varacin
Wikidata:Q3034003
Metabolomics Workbench ID:123570
ChEMBL ID:CHEMBL151233
Mol file:134029-48-4.mol

Synonyms:VARACIN;Varacine;134029-48-4;6-Benzopentathiepinethanamine, 8,9-dimethoxy-;CHEMBL151233;2-(6,7-dimethoxy-1,2,3,4,5-benzopentathiepin-9-yl)ethanamine;85V98E6A3M;1,2,3,4,5-Benzopentathiepin-6-ethanamine, 8,9-dimethoxy-;barazi n;UNII-85V98E6A3M;DTXSID10158465;BDBM50240848;Q3034003;8,9-DIMETHOXY-1,2,3,4,5-BENZOPENTATHIEPIN-6-ETHANAMINE;2-(3,4-Dimethoxy-5,6,7,8,9-pentathia-benzocyclohepten-1-yl)-ethylamine

Suppliers and Price of Varacin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Varacin

Chemical Property:

Vapor Pressure:1.32E-11mmHg at 25°C
Boiling Point:537°Cat760mmHg
Flash Point:278.6°C
PSA：170.98000
Density:1.439g/cm³
LogP:4.96270
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:338.95498453
Heavy Atom Count:18
Complexity:260

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C(C(=C1)CCN)SSSSS2)OC

Technology Process of Varacin

There total 11 articles about Varacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 165258-79-7
N-(t-butyloxycarbonyl)varacin

: 134029-48-4
varacin

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 1.5h;
DOI:10.1016/S0040-4020(02)01296-6

Reference yield:

: 149625-17-2
6,7-Dimethoxy-9-<2-<<<2-(trimethylsilyl)ethoxy>carbonyl>amino>ethyl>benzopentathiepin

: 134029-48-4
varacin

Guidance literature:: With trifluoroacetic acid; In chloroform; Yield given;
DOI:10.1021/jo00069a006

Reference yield:

: 2973-76-4
5-bromo-4-hydroxy-3-methoxybenzaldehyde

: 134029-48-4
varacin

Guidance literature:: Multi-step reaction with 8 steps

1: 99 percent / aq. K₂CO₃, n-Bu₄NI / tetrahydrofuran

2: 51 percent / Br₂ / acetic acid / 60 °C

3: 1.) quinoline, pyridine, 2.) aq. K₂CO₃, n-Bu₄NI / 1.) 160 deg C, 2.) CH₂Cl₂

4: 74 percent / NH₄OAc / acetic acid

5: LiAlH₄ / tetrahydrofuran / Heating

6: Et₃N / CH₂Cl₂

7: 28 percent / 1.) Na, NH₃, 2.) S₂Cl₂ / 2.) THF

8: TFA / CHCl₃

With pyridine; quinoline; disulfur dichloride; lithium aluminium tetrahydride; ammonium acetate; ammonia; bromine; sodium; tetra-(n-butyl)ammonium iodide; potassium carbonate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; chloroform; acetic acid;
DOI:10.1021/jo00069a006