9H-Xanthen-9-one, 2-phenyl-

Base Information

• Chemical Name: 9H-Xanthen-9-one, 2-phenyl-
• CAS No.: 50781-46-9
• Molecular Formula: C19H12O2
• Molecular Weight: 272.303
• Mol file: 50781-46-9.mol

Synonyms:

Chemical Property of 9H-Xanthen-9-one, 2-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9H-Xanthen-9-one, 2-phenyl-

There total 13 articles about 9H-Xanthen-9-one, 2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-bromo-9H-xanthene-9-one (56341-31-2) + phenylboronic acid (98-80-6) → 2-phenyl-9H-xanthen-9-one (50781-46-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; at 20 ℃; for 2h; Inert atmosphere; Reflux;

DOI:10.3987/COM-11-12162

Reference yield: 80.0%

2-(biphenyl-4-yloxy)benzaldehyde (934691-77-7) → 2-phenyl-9H-xanthen-9-one (50781-46-9)

Guidance literature:

With carbon tetrabromide; oxygen; In neat (no solvent); at 140 ℃;

DOI:10.1039/c7ob00080d

Reference yield: 80.0%

(2-bromophenyl)(4-hydroxy-[1,1’-biphenyl]-3-yl)methanone → 2-phenyl-9H-xanthen-9-one (50781-46-9)

Guidance literature:

With potassium hydroxide; In water; at 100 ℃; for 5h;

DOI:10.1002/adsc.201800462

upstream raw materials:

methyl 4-hydroxy-[1,1’-biphenyl]-3-carboxylate

2-(trimethylsilyl)phenyl trifluoromethanesulfonate

2-(biphenyl-4-yloxy)benzaldehyde

4-Phenylphenol

Downstream raw materials:

C₁₉H₁₃NO₂

C₁₉H₁₃NO₂

C₂₆H₂₀N₂O₃

2-hydroxy-5-phenyl-2'-hydroxybenzophenone

Refernces

• 1、 Bao, Hanyang,Hu, Xiaojun,Zhang, Jian,Liu, Yunkui. "Cu(0)/Selectfluor system-catalyzed intramolecular Csp2-H/Csp2-H cross-dehydrogenative coupling (CDC)". . . Retrieved 2019/09/30.
• 2、 Tang, Jing,Zhao, Shijun,Wei, Yuanyuan,Quan, Zhengjun,Huo, Congde. "CBr4 promoted intramolecular aerobic oxidative dehydrogenative arylation of aldehydes: application in the synthesis of xanthones and fluorenones". supporting information. p. 1589 - 1592. Retrieved 2017/02/23.