Carbamic acid, [(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-, (1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl ]propyl ester

Base Information

Chemical Name:Carbamic acid, [(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-, (1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl ]propyl ester
CAS No.:511268-28-3
Molecular Formula:C₂₉H₃₈F₃N₅O₅S
Molecular Weight:625.712
Hs Code.:
Mol file:511268-28-3.mol

Carbamic acid,
[(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-,
(1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl
]propyl ester

Synonyms:

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Chemical Property of Carbamic acid, [(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-, (1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl ]propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-, (1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl ]propyl ester

There total 5 articles about Carbamic acid, [(1S)-1-[1-hydroxy-2-[(2-pyridinylsulfonyl)amino]ethyl]pentyl]-, (1S)-2,2-dimethyl-1-[[3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-yl]methyl ]propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104062-70-6,440125-24-6
(S)-N-Boc-leucinal

: 511268-28-3
{(S)-1-[1-Hydroxy-2-(pyridine-2-sulfonylamino)-ethyl]-pentyl}-carbamic acid (S)-2,2-dimethyl-1-[3-(4-trifluoromethyl-phenyl)-pyrazol-1-ylmethyl]-propyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: HOAc / methanol

2: H₂; HOAc / PtO₂/C

3: NaHCO₃ / CH₂Cl₂; H₂O

4: 99 percent / HCl / dioxane

5: i-Pr₂NEt / dimethylformamide

With hydrogenchloride; hydrogen; sodium hydrogencarbonate; acetic acid; N-ethyl-N,N-diisopropylamine; PtO₂/C; In 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.10.102

Reference yield:

: 274685-84-6
[1-(cyano-hydroxy-methyl)-pentyl]-carbamic acid tert-butyl ester

: 511268-28-3
{(S)-1-[1-Hydroxy-2-(pyridine-2-sulfonylamino)-ethyl]-pentyl}-carbamic acid (S)-2,2-dimethyl-1-[3-(4-trifluoromethyl-phenyl)-pyrazol-1-ylmethyl]-propyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂; HOAc / PtO₂/C

2: NaHCO₃ / CH₂Cl₂; H₂O

3: 99 percent / HCl / dioxane

4: i-Pr₂NEt / dimethylformamide

With hydrogenchloride; hydrogen; sodium hydrogencarbonate; acetic acid; N-ethyl-N,N-diisopropylamine; PtO₂/C; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.10.102

Reference yield:

: 511268-25-0
[1-(2-amino-1-hydroxy-ethyl)-pentyl]-carbamic acid tert-butyl ester

: 511268-28-3
{(S)-1-[1-Hydroxy-2-(pyridine-2-sulfonylamino)-ethyl]-pentyl}-carbamic acid (S)-2,2-dimethyl-1-[3-(4-trifluoromethyl-phenyl)-pyrazol-1-ylmethyl]-propyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: NaHCO₃ / CH₂Cl₂; H₂O

2: 99 percent / HCl / dioxane

3: i-Pr₂NEt / dimethylformamide

With hydrogenchloride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2006.10.102