Uridine, 5-(trimethylsilyl)-

Base Information

Chemical Name:Uridine, 5-(trimethylsilyl)-
CAS No.:51432-36-1
Molecular Formula:C12H20N2O6Si
Molecular Weight:316.38300
Hs Code.:
DSSTox Substance ID:DTXSID70550709
Wikidata:Q82430137
Mol file:51432-36-1.mol

Synonyms:Uridine, 5-(trimethylsilyl)-;51432-36-1;5-Trimethylsilyluridine;5-(Trimethylsilyl)uridine;DTXSID70550709;JUUZWFQWLBMRHS-PNHWDRBUSA-N

Suppliers and Price of Uridine, 5-(trimethylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Uridine, 5-(trimethylsilyl)-

Chemical Property:

PSA：125.04000
LogP:-1.89440
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:316.10906290
Heavy Atom Count:21
Complexity:489

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
Isomeric SMILES:C[Si](C)(C)C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Technology Process of Uridine, 5-(trimethylsilyl)-

There total 3 articles about Uridine, 5-(trimethylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 110522-96-8
1-[(2R,3R,4R,5R)-3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-trimethylsilanyl-1H-pyrimidine-2,4-dione

: 51432-36-1
5-Trimethylsilyl-uridin

Guidance literature:: With trifluoroacetic acid; In chloroform;
DOI:10.1016/S0040-4039(00)95656-9

Reference yield:

: 64898-15-3
2',3',5'-tris-O-(tert-butyldimethylsilyl)uridine

: 51432-36-1
5-Trimethylsilyl-uridin

Guidance literature:: Multi-step reaction with 2 steps

1: 1) sec-BuLi, TMEDA / 1) THF, -70 deg C, 2 h

2: 54 percent / 50percent aqueous trifluoroacetic acid / CHCl₃

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; trifluoroacetic acid; In chloroform;
DOI:10.1016/S0040-4039(00)95656-9