3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE

Base Information

• Chemical Name: 3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE
• CAS No.: 521917-61-3
• Molecular Formula: C10H8BrCl
• Molecular Weight: 243.52800
• Mol file: 521917-61-3.mol

Synonyms:3-Bromo-6-chloro-1,2-dihydro-naphthalene;

Chemical Property of 3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE

Chemical Property:

• PSA: 0.00000
• LogP: 4.02200

Purity/Quality:

3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE

There total 3 articles about 3-BROMO-6-CHLORO-1,2-DIHYDRONAPHTHALENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-chloro-3,4-dihydro-2H-naphthalen-1-one (26673-32-5) → 3-bromo-6-chloro-1,2-dihydro-naphthalene (521917-61-3)

Guidance literature:

Multi-step reaction with 3 steps

1: Br₂ / diethyl ether / 10 °C

2: NaBH₄ / ethanol; tetrahydrofuran / 20 °C

3: p-TsOH / toluene / 120 °C

With sodium tetrahydroborate; bromine; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; ethanol; toluene;

DOI:10.2533/000942904777677579

Reference yield:

2-bromo-7-chloro-1,2,3,4-tetrahydro-naphthalen-1-ol → 3-bromo-6-chloro-1,2-dihydro-naphthalene (521917-61-3)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 120 ℃;

DOI:10.2533/000942904777677579

Reference yield:

2-Bromo-7-chloro-l-tetralone (56820-57-6) → 3-bromo-6-chloro-1,2-dihydro-naphthalene (521917-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / ethanol; tetrahydrofuran / 20 °C

2: p-TsOH / toluene / 120 °C

With sodium tetrahydroborate; toluene-4-sulfonic acid; In tetrahydrofuran; ethanol; toluene;

DOI:10.2533/000942904777677579

upstream raw materials:

7-chloro-3,4-dihydro-2H-naphthalen-1-one

2-Bromo-7-chloro-l-tetralone