6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol

Base Information

Chemical Name:6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol
CAS No.:64309-39-3
Molecular Formula:C₁₆H₂₅NO₂
Molecular Weight:263.38
Hs Code.:2922299090
DSSTox Substance ID:DTXSID90982861
Nikkaji Number:J376.262I
Pharos Ligand ID:6QGHXU9UJYPB
ChEMBL ID:CHEMBL11845
Mol file:64309-39-3.mol

Synonyms:2-(N,N-dipropyl)amino-5,6-dihydroxytetralin;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, (+-)-isomer;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, (R)-isomer;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, (S)-isomer;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, hydrobromide;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, hydrochloride;2-(N,N-dipropyl)amino-5,6-dihydroxytetralin, hydrochloride, (+-)-isomer;5,6-dihydroxy-2-N,N-dipropylaminotetralin;N,N-dipropyl-5,6-ADTN;TL 102 (pharmaceutical)

Suppliers and Price of 6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol

Chemical Property:

Vapor Pressure:1.95E-07mmHg at 25°C
Boiling Point:413.8°C at 760 mmHg
PKA:10.24±0.40(Predicted)
Flash Point:202.2°C
PSA：43.70000
Density:1.11g/cm³
LogP:3.07710
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:263.188529040
Heavy Atom Count:19
Complexity:266

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCN(CCC)C1CCC2=C(C1)C=CC(=C2O)O

Technology Process of 6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol

There total 3 articles about 6-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58352-86-6,88193-08-2,94844-53-8
(+/-)-5,6-dimethoxy-2-(N,N-di-n-propylamino)tetralin

: 64309-39-3
5,6-dihydroxy-2-di-n-propylamino-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With hydrogen iodide; acetic anhydride; Heating;
DOI:10.1021/jm00238a008

Reference yield:

: 52644-01-6
5,6-dimethoxy-2-tetralone

: 64309-39-3
5,6-dihydroxy-2-di-n-propylamino-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 2 steps

1: (i) TsOH, benzene, (ii) H₂, PtO₂, EtOH

2: aq. HI, Ac₂O / Heating

With hydrogen iodide; acetic anhydride;
DOI:10.1021/jm00238a008

Reference yield:

: 55218-06-9
1,2,6-trimethoxynaphthalene

: 64309-39-3
5,6-dihydroxy-2-di-n-propylamino-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 3 steps

1: Na, EtOH

2: (i) TsOH, benzene, (ii) H₂, PtO₂, EtOH

3: aq. HI, Ac₂O / Heating

With ethanol; hydrogen iodide; sodium; acetic anhydride;
DOI:10.1021/jm00238a008