Dimethyl isopropylidenesuccinate, tech.

Base Information

• Chemical Name: Dimethyl isopropylidenesuccinate, tech.
• CAS No.: 87384-00-7
• Molecular Formula: C₉H₁₄O₄
• Molecular Weight: 186.208
• Mol file: 87384-00-7.mol

Synonyms:

Chemical Property of Dimethyl isopropylidenesuccinate, tech.

Chemical Property:

• Vapor Pressure: 0.0388mmHg at 25°C
• Boiling Point: 240°Cat760mmHg
• Flash Point: 111°C
• PSA: 52.60000
• Density: 1.05g/cm³
• LogP: 1.05890

Purity/Quality:

98%Min ^*data from raw suppliers

Dimethyl isopropylidenesuccinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dimethyl isopropylidenesuccinate, tech.

There total 4 articles about Dimethyl isopropylidenesuccinate, tech. which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

di-isopropyl ether (108-20-3) + dimethyl cis-but-2-ene-1,4-dioate (624-48-6) → 2-isopropylbutanedioic acid 1,4-dimethyl ester (23292-51-5) + 2-isopropenylbutanedioic acid 1,4-dimethyl ester (87384-00-7)

Guidance literature:

With di-tert-butyl peroxide; at 20 ℃; for 3h; Inert atmosphere; UV-irradiation;

DOI:10.1016/j.tet.2020.131557

Reference yield:

2,2-dichloropropane (594-20-7) + dimethylfumarate (624-49-7) → dimethyl trans-3,3-dimethylxyclopropane-1,2-dicarboxylate (16601-23-3) + 2-isopropenylbutanedioic acid 1,4-dimethyl ester (87384-00-7) + Dimethyl succinate (106-65-0)

Guidance literature:

With cobalt chloride; sodium iodide; zinc; Yield given. Yields of byproduct given; 1.) acetonitrile, RT, 2.) acetonitrile, RT, 64 h;

DOI:10.1246/bcsj.56.1592

Reference yield:

2,2-dibromopropane (594-16-1) + dimethylfumarate (624-49-7) → dimethyl trans-3,3-dimethylxyclopropane-1,2-dicarboxylate (16601-23-3) + 2-isopropenylbutanedioic acid 1,4-dimethyl ester (87384-00-7) + Dimethyl succinate (106-65-0)

Guidance literature:

With sodium iodide; nickel dibromide; zinc; Yield given. Yields of byproduct given; 1.) acetonitrile, RT, 2.) acetonitrile, RT, 27 h;

DOI:10.1246/bcsj.56.1592

upstream raw materials:

2,2-dibromopropane

dimethyl cis-but-2-ene-1,4-dioate

2,2-dichloropropane

dimethylfumarate

Refernces

• 1、 Kanai,Nishiguchi,Matsuda. "CYCLOPROPANATION OF DIMETHYL FUMARATE AND MALEATE WITH GEM-DIHALIDES CATALYZED BY Co(0)- OR Ni(0)-COMPLEX AND ZINC.". . p. 1592 - 1597. Retrieved 2007/10/02.