1,3-Benzodioxole-5-carbonitrile, 6-nitro-

Base Information

Chemical Name:1,3-Benzodioxole-5-carbonitrile, 6-nitro-
CAS No.:52805-38-6
Molecular Formula:C8H4N2O4
Molecular Weight:192.12800
Hs Code.:
Mol file:52805-38-6.mol

Synonyms:6-Nitro-benzo[1,3]dioxole-5-carbonitrile;3,4-Methylendioxy-6-nitro-benzonitril;6-Nitro-benzo[1,3]dioxol-5-carbonitril;

Suppliers and Price of 1,3-Benzodioxole-5-carbonitrile, 6-nitro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1,3-Benzodioxole-5-carbonitrile, 6-nitro-

Chemical Property:

Melting Point:144 - 145 °C
PSA：88.07000
LogP:1.71838

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,3-Benzodioxole-5-carbonitrile, 6-nitro-

There total 1 articles about 1,3-Benzodioxole-5-carbonitrile, 6-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 98606-60-1
6-nitro-benzo[1,3]dioxole-5-carbaldehyde-phenylhydrazone

: 52805-38-6
6-nitro-1,3-benzodioxole-5-carbonitrile

: 7684-30-2
N,N-dimethyl-N'-phenylcarbamimidic chloride

Guidance literature:: With dichloromethylenedimethyliminium chloride; In 1,2-dichloro-ethane; 1.) room temp., 1 h, 2.) reflux, 4 h;
DOI:10.1055/s-1985-31154

Reference yield:

: 52805-38-6
6-nitro-1,3-benzodioxole-5-carbonitrile

: 656833-98-6
6-(4-amino-phenyl)-7H-[1,3]dioxolo[4,5-g]quinazolin-8-one

Guidance literature:: Multi-step reaction with 4 steps

1: percarbamide; aq. Na₂CO₃ / acetone / 18 h / 20 °C

2: HCOONH₄; Raney-Ni / methanol / 2 h / Heating

3: p-TsOH / benzene / Heating

4: Zn; aq. NH₄Cl / ethanol / 1 h / 20 °C

With percarbamide; ammonium formate; nickel; sodium carbonate; ammonium chloride; toluene-4-sulfonic acid; zinc; In methanol; ethanol; acetone; benzene;
DOI:10.1016/j.bmcl.2003.09.032

Reference yield:

: 52805-38-6
6-nitro-1,3-benzodioxole-5-carbonitrile

: 6-(4-amino-phenyl)-7H-[1,3]dioxolo[4,5-g]quinazoline-8-thione

Guidance literature:: Multi-step reaction with 5 steps

1: percarbamide; aq. Na₂CO₃ / acetone / 18 h / 20 °C

2: HCOONH₄; Raney-Ni / methanol / 2 h / Heating

3: p-TsOH / benzene / Heating

4: Zn; aq. NH₄Cl / ethanol / 1 h / 20 °C

5: Lawesson's reagent / dioxane / 24 h / Heating

With Lawessons reagent; percarbamide; ammonium formate; nickel; sodium carbonate; ammonium chloride; toluene-4-sulfonic acid; zinc; In 1,4-dioxane; methanol; ethanol; acetone; benzene;
DOI:10.1016/j.bmcl.2003.09.032