N-Phenyl-guanosine 2',3',5'-Triacetate

Base Information

• Chemical Name: N-Phenyl-guanosine 2',3',5'-Triacetate
• CAS No.: 53296-13-2
• Molecular Formula: C22H23N5O8
• Molecular Weight: 485.44700
• Mol file: 53296-13-2.mol

Synonyms:[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-anilino-6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl acetate;

Chemical Property of N-Phenyl-guanosine 2',3',5'-Triacetate

Chemical Property:

• PSA: 167.22000
• LogP: 1.02130
• Solubility.: Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol

Purity/Quality:

95% ^*data from raw suppliers

N-PhenylGuanosine2'',3'',5''-Triacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-Phenyl-guanosine 2',3',5'-Triacetate is used in the synthesis of C-2 substituted adenosines.

Technology Process of N-Phenyl-guanosine 2',3',5'-Triacetate

There total 3 articles about N-Phenyl-guanosine 2',3',5'-Triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O2',O3',O5'-triacetyl-2-bromo-inosine (41623-91-0) → O2',O3',O5'-triacetyl-N2-phenyl-guanosine (53296-13-2)

Guidance literature:

With aniline; In methanol;

Reference yield:

→ 2-phenylaminoinosine-triacetate (53296-13-2)

Guidance literature:

2-Phenylaminoinosin (30), Ac2O;

DOI:10.1248/cpb.23.759

Reference yield:

→ O2',O3',O5'-triacetyl-N2-phenyl-guanosine (53296-13-2)

Guidance literature:

2-Bromverb., Anilin;

upstream raw materials:

O^2'_,O3'_,O5'-triacetyl-2-bromo-inosine

Downstream raw materials:

Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-phenylamino-6-thioxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester

6-methythio-2-phenylamino-9-(β-D-ribofuranosyl)purine

6-mercapto-2-phenylamino-9-(β-D-ribofuranosyl)purine

2-phenylaminoadenosine

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