1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]-

Base Information

Chemical Name:1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]-
CAS No.:534596-12-8
Molecular Formula:C17H15NO3
Molecular Weight:281.30600
Hs Code.:
Mol file:534596-12-8.mol

Synonyms:1H-Indole-2-carboxylic acid,1-[(3-methoxyphenyl)methyl];1-(3-Methoxy-benzyl)-1H-indole-2-carboxylic acid;

Suppliers and Price of 1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]-

Chemical Property:

Boiling Point:527.2±35.0 °C(Predicted)
PSA：51.46000
Density:1.21±0.1 g/cm3(Predicted)
LogP:3.39640

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]-

There total 6 articles about 1H-Indole-2-carboxylic acid, 1-[(3-methoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(3-methoxy-benzyl)-1H-indole-2-carboxylic acid methyl ester

: 534596-12-8
1-(3-Methoxy-benzyl)-1H-indole-2-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; at 60 ℃;
DOI:10.1021/jm0490540

Reference yield:

: 754199-24-1
1-(3-methoxy-benzyl)-1H-indole-2-carboxylic acid ethyl ester

: 534596-12-8
1-(3-Methoxy-benzyl)-1H-indole-2-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; at 60 ℃; for 2h;
DOI:10.1016/j.bmcl.2004.06.020

Reference yield:

Indole-2-carboxylic acid: 1477-50-5,1228050-17-6
Indole-2-carboxylic acid

: 534596-12-8
1-(3-Methoxy-benzyl)-1H-indole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: HCl / 16 h / 20 °C

2.1: NaH / dimethylformamide / 20 °C

2.2: dimethylformamide / 80 °C

3.1: lithium hydroxide monohydrate / tetrahydrofuran / 60 °C

With hydrogenchloride; lithium hydroxide; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm0490540