2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid

Base Information

Chemical Name:2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid
CAS No.:13081-15-7
Molecular Formula:C11H12 N2 O4
Molecular Weight:236.227
Hs Code.:
Nikkaji Number:J922.906J

Synonyms:SCHEMBL1520966

Suppliers and Price of 2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.388g/cm³
XLogP3:-2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:236.07970687
Heavy Atom Count:17
Complexity:346

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C(=O)N2)(CC(C(=O)O)N)O

Technology Process of 2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid

There total 13 articles about 2-amino-3-(3-hydroxy-2-oxo-1H-indol-3-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 3.0%

: 73-22-3,6912-86-3,54-12-6,153-94-6,63148-28-7,65556-72-1,27732-43-0,80206-30-0,27813-82-7
L-tryptophan

: 6536-35-2
oxindolyl-L-alanine

: 13081-15-7,76604-82-5,76604-83-6,128303-30-0,128357-72-2,184955-21-3
dioxindolyl-L-alanine

Guidance literature:: With hydrogenchloride; dimethyl sulfoxide; phenol; In acetic acid; for 5h; Ambient temperature;
DOI:10.1021/jo00303a027

Reference yield:

: 32999-55-6,105016-76-0,105016-77-1
2-Amino-3-(2-oxo-2,3-dihydro-1H-indol-3-yl)-propionic acid

: 343-65-7,2922-83-0,3039-10-9,13441-51-5
L-kynurenine

: 13081-15-7,184955-21-3
2-amino-3-(3-hydroxy-2-oxo-2,3-dihydro-indol-3-yl)-propionic acid

Guidance literature:: With sodium hydroxide; dimethylsulfide; Yield given. Multistep reaction; 1.) 4 h, room temp.;
DOI:10.1016/S0040-4039(00)98249-2

Reference yield:

: 13081-15-7,184955-21-3
2-amino-3-(3-hydroxy-2-oxo-2,3-dihydro-indol-3-yl)-propionic acid

Guidance literature:: With hydrogenchloride; methanol; palladium; optically inactive stereoisomer(ic) of mp: 259 degree; Hydrogenation;
DOI:10.1021/ja01595a064