3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)-

Base Information

Chemical Name:3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)-
CAS No.:536972-31-3
Molecular Formula:C38H43N3O5
Molecular Weight:621.777
Hs Code.:

3-Oxazolidinecarboxylic acid,
5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro-
1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth
yl)-, 1,1-dimethylethyl ester, (4S,5S)-

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Suppliers and Price of 3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)-

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Chemical Property of 3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)-

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Technology Process of 3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)-

There total 8 articles about 3-Oxazolidinecarboxylic acid, 5-[[(2S)-2,3-dihydro-3-oxo-2-(phenylmethyl)-4-[(4R)-1,2,3,4-tetrahydro- 1-oxo-4-isoquinolinyl]-1H-pyrrol-2-yl]methyl]-2,2-dimethyl-4-(phenylmeth yl)-, 1,1-dimethylethyl ester, (4S,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (4S,5S)-4-Benzyl-5-{(S)-2-methoxycarbonyl-2-[2-((S)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl)-eth-(E)-ylideneamino]-3-phenyl-propyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 536972-31-3
(4S,5S)-4-Benzyl-5-[(S)-2-benzyl-3-oxo-4-((R)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl)-2,3-dihydro-1H-pyrrol-2-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: With potassium hexamethylsilazane; In tetrahydrofuran; toluene; for 0.333333h;
DOI:10.1021/jm0204587

Reference yield:

: 173240-65-8
(4S,5S)-5-((S)-2-Amino-2-methoxycarbonyl-3-phenyl-propyl)-4-benzyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 536972-31-3
(4S,5S)-4-Benzyl-5-[(S)-2-benzyl-3-oxo-4-((R)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl)-2,3-dihydro-1H-pyrrol-2-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene

2: 52 mg / KHMDS / tetrahydrofuran; toluene / 0.33 h

With potassium hexamethylsilazane; In tetrahydrofuran; toluene;
DOI:10.1021/jm0204587

Reference yield:

: 536972-30-2
((S)-1-Oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl)-acetaldehyde

: 536972-31-3
(4S,5S)-4-Benzyl-5-[(S)-2-benzyl-3-oxo-4-((R)-1-oxo-1,2,3,4-tetrahydro-isoquinolin-4-yl)-2,3-dihydro-1H-pyrrol-2-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene

2: 52 mg / KHMDS / tetrahydrofuran; toluene / 0.33 h

With potassium hexamethylsilazane; In tetrahydrofuran; toluene;
DOI:10.1021/jm0204587