1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)-

Base Information

• Chemical Name: 1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)-
• CAS No.: 2562-81-4
• Molecular Formula: C17H12 N2
• Molecular Weight: 244.296
• Hs Code.: 2934999090
• Mol file: 2562-81-4.mol

Synonyms:Benzimidazole,2-(1-naphthyl)- (6CI,7CI,8CI); 2-(1-Naphthyl)benzimidazole; NSC 144033

Chemical Property of 1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)-

Chemical Property:

• Vapor Pressure: 9.06E-10mmHg at 25°C
• Boiling Point: 490.5°Cat760mmHg
• Flash Point: 274°C
• PSA: 28.68000
• Density: 1.256g/cm³
• LogP: 4.38310

Purity/Quality:

99% ^*data from raw suppliers

2-(NAPHTHALEN-1-YL)-1H-1,3-BENZODIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)-

There total 24 articles about 1H-BENZIMIDAZOLE, 2-(1-NAPHTHALENYL)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-naphthaldehyde (66-77-3) + 1,2-diamino-benzene (95-54-5) → 2-(naphthalen-1-yl)-1H-benzo[d]imidazole (2562-81-4)

Guidance literature:

With sodium metabisulfite; In N,N-dimethyl-formamide; at 80 ℃; for 0.4h; Microwave irradiation;

DOI:10.1002/jhet.1058

Reference yield: 98.0%

N-(2-nitrophenyl)naphthalene-1-carboxamide (461032-31-5) → 2-(naphthalen-1-yl)-1H-benzo[d]imidazole (2562-81-4)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 10% palladium on activated carbon; In acetic acid; at 120 ℃; for 15h; Inert atmosphere;

DOI:10.1002/ejoc.201000985

Reference yield: 97.0%

1-naphthaldehyde (66-77-3) + 2-nitro-aniline (88-74-4) → 2-(naphthalen-1-yl)-1H-benzo[d]imidazole (2562-81-4)

Guidance literature:

With hydrogen; In ethyl acetate; at 100 ℃; for 20h; under 7500.75 Torr; Temperature; Autoclave; Green chemistry;

DOI:10.1002/cssc.202002344

upstream raw materials:

1-naphthalenecarboxylic acid

1,2-diamino-benzene

1-naphthalenedithiocarboxylic acid

(E)-2-(1H-Benzoimidazol-2-yl)-3-naphthalen-1-yl-acrylonitrile

Downstream raw materials:

3-chloro-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline

1-chloro-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline

1-methyl-6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline

6-phenylbenzo[4,5]imidazo[2,1-a]isoquinoline-3-carbonitrile