(2-Methylphenyl)phosphane

Base Information

• Chemical Name: (2-Methylphenyl)phosphane
• CAS No.: 53772-59-1
• Molecular Formula: C7H9P
• Molecular Weight: 124.122
• DSSTox Substance ID: DTXSID00567542
• Wikidata: Q82453452
• Mol file: 53772-59-1.mol

Synonyms:(2-Methylphenyl)phosphane;tolylphosphine;o-tolylphosphine;53772-59-1;o-Tolyl-phosphane;ortho-tolylphosphine;SCHEMBL67348;SCHEMBL11582256;DTXSID00567542;KYLUAQBYONVMCP-UHFFFAOYSA-N

Chemical Property of (2-Methylphenyl)phosphane

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 124.044187285
• Heavy Atom Count: 8
• Complexity: 70.8

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1P

Technology Process of (2-Methylphenyl)phosphane

There total 2 articles about (2-Methylphenyl)phosphane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-methylphenyl bromide (95-46-5) → ortho-tolylphosphine (53772-59-1)

Guidance literature:

2-methylphenyl bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere; Schlenk technique; Glovebox;

With zinc(II) chloride; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Further stages; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1021/acs.organomet.8b00480

Reference yield:

→ ortho-tolylphosphine (53772-59-1)

Guidance literature:

aus o-Tolyl-dichlor-phosphin mit LiAlH4;

DOI:10.1002/hlca.19670500706

Reference yield: 85.0%

methyl 4,6-O-benzylidene-2,3-anhydro-α-D-mannopyranoside (3150-16-1) + ortho-tolylphosphine (53772-59-1) → (methyl 3-deoxy-4,6-oxo-benzylidene-α-D-azopyranosidyl-3)-(2-methylphenyl)phosphine

Guidance literature:

ortho-tolylphosphine; In tetrahydrofuran; hexane; at 20 ℃; for 2h; Schlenk technique; Inert atmosphere;

methyl 4,6-O-benzylidene-2,3-anhydro-α-D-mannopyranoside; In tetrahydrofuran; for 6h; Schlenk technique;

upstream raw materials:

2-methylphenyl bromide

Downstream raw materials:

{(2-methylphenyl)phosphine}gold(I) bromide {(2-Methylphenyl)phosphin}gold(I)-bromid

(2-methylphenyl)tetrakis{(triphenylphosphine)aurio(I)}phosphonium⁽²⁺⁾ bis(tetrafluoroborate)