6-Amino-1,3-dimethyl-5-phenylazouracil

Base Information

• Chemical Name: 6-Amino-1,3-dimethyl-5-phenylazouracil
• CAS No.: 54014-80-1
• Molecular Formula: C12H13N5O2
• Molecular Weight: 259.268
• Hs Code.: 2933599090
• Mol file: 54014-80-1.mol

Synonyms:2,4(1H,3H)-Pyrimidinedione,6-amino-1,3-dimethyl-5-(phenylazo);

Chemical Property of 6-Amino-1,3-dimethyl-5-phenylazouracil

Chemical Property:

• PSA: 88.86000
• LogP: 1.00410

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-Amino-1,3-dimethyl-5-phenylazouracil

There total 1 articles about 6-Amino-1,3-dimethyl-5-phenylazouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

6-Amino-1,3-dimethylbarbituric acid (6642-31-5) + aniline (62-53-3) → 1,3-dimethyl-5-(phenylazo)-6-aminouracil (54014-80-1)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 - 60 ℃; for 2.25h;

DOI:10.1016/j.tetlet.2017.07.027

Reference yield: 82.0%

nickel(II) chloride hexahydrate + 1,3-dimethyl-5-(phenylazo)-6-aminouracil (54014-80-1) → bis[1,3-dimethyl-5-(phenylazo)-6-aminouracilato]nickel(II)

Guidance literature:

With sodium hydrogencarbonate; In water; N,N-dimethyl-formamide; at 110 ℃; for 2h;

DOI:10.1002/ejic.201601021

Reference yield: 80.0%

potassium tetrachloropalladate(II) (10025-98-6) + 1,3-dimethyl-5-(phenylazo)-6-aminouracil (54014-80-1) → trans-bis(1,3-dimethyl-2,4-dioxo-5-phenylazo-κN'-pyrimidin-6-yl-amido-κN)palladium(II) (131862-81-2)

Guidance literature:

In ethanol; water; Addn. of uracil derivative to a stirred, heated soln. of K2(PdCl4) in ethanol-H2O, refluxing (1 h).; Filtn. of ppt., washing (ethanol), drying with diethyl ether, elem. anal.;

DOI:10.1039/DT9900002747

upstream raw materials:

6-Amino-1,3-dimethylbarbituric acid

aniline

Downstream raw materials:

trans-bis(1,3-dimethyl-2,4-dioxo-5-phenylazo-κN'-pyrimidin-6-yl-amido-κN)palladium(II)

4,6-dimethyl-2-phenyl-4,5,6,7-tetrahydro-2H-1,2,3-triazolo[4,5-d]pyrimidine-5,7-dione

Refernces

• 1、 Debnath, Diptanu,Roy, Subhadip,Li, Bing-Han,Lin, Chia-Her,Misra, Tarun Kumar. "Synthesis, structure and study of azo-hydrazone tautomeric equilibrium of 1,3-dimethyl-5-(arylazo)-6-amino-uracil derivatives". . p. 185 - 197. Retrieved 2015/01/30.