gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid

Base Information

• Chemical Name: gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid
• CAS No.: 39241-36-6
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.301
• ChEMBL ID: CHEMBL1204600
• DSSTox Substance ID: DTXSID30960007
• Nikkaji Number: J394.884F
• Mol file: 39241-36-6.mol

Synonyms:39241-36-6;gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid;(1,1'-Biphenyl)-4-butanoic acid, gamma-hydroxy-;gamma-Hydroxy-4-biphenylbutyric acid;HBBA;SCHEMBL7345068;CHEMBL1204600;DTXSID30960007;NJGRSTRMISTCEB-UHFFFAOYSA-N;AKOS009116290;4-(4-biphenylyl)-4-hydroxybutyric acid;4-([1,1'-Biphenyl]-4-yl)-4-hydroxybutanoic acid

Chemical Property of gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid

Chemical Property:

• PSA: 57.53000
• LogP: 3.25180
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 276

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C(CCC(=O)O)O

Technology Process of gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid

There total 1 articles about gamma-Hydroxy-(1,1'-biphenyl)-4-butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(p-phenyl)benzoylpropionic acid (36330-85-5) → dl-4-(4-Biphenylyl)-4-hydroxybutyric acid (39241-36-6,63472-10-6,63472-11-7) + 5-(1,1'-biphenyl)-4-yldihydro-2(3H)-furanone (40885-19-6)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 0 - 20 ℃;

DOI:10.1021/jm801112u

Reference yield:

dl-4-(4-Biphenylyl)-4-hydroxybutyric acid (39241-36-6,63472-10-6,63472-11-7) → 5-(1,1'-biphenyl)-4-yldihydro-2(3H)-furanone (40885-19-6)

Guidance literature:

With acid;

upstream raw materials:

3-(p-phenyl)benzoylpropionic acid

Downstream raw materials:

5-(1,1'-biphenyl)-4-yldihydro-2(3H)-furanone

Refernces