Synonyms:(2-Cyclohexyl-2-phenyl-ethyl)-(1-methyl-2-phenyl-ethyl)-amine;1-Phenyl-2-<2-cyclohexyl-2-phenyl-aethylamino>-propan;1-Phenyl-2-(2-cyclohexyl-2-phenyl-aethylamino)-propan;
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There total 2 articles about N-(α-Methylphenethyl)-β-phenylcyclohexaneethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
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The study focuses on the discovery and exploration of octahydrophenanthrene-2,7-diol analogues as dissociated glucocorticoid receptor (GR) agonists. These compounds are designed to selectively activate the GR, retaining potent anti-inflammatory activity through transrepression while reducing side effects associated with transactivation. The research involves the synthesis and evaluation of various chemical analogues, with the aim of improving chemical stability, reducing the likelihood of toxic metabolites, and enhancing the drugs' therapeutic index. Key chemicals used in the study include octahydrophenanthrene-2,7-diol analogues, their derivatives, and organometallic reagents for chemical modifications. These chemicals serve to modulate the GR pathway, potentially leading to the development of new anti-inflammatory drugs with reduced side effects.
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