Isoindolin-5-ol

Base Information

Chemical Name:Isoindolin-5-ol
CAS No.:54544-67-1
Molecular Formula:C8H9NO
Molecular Weight:135.16300
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40595324
Wikidata:Q82490320
Mol file:54544-67-1.mol

Synonyms:Isoindolin-5-ol;54544-67-1;2,3-Dihydro-1H-isoindol-5-ol;5-hydroxyisoindoline;1H-Isoindol-5-ol, 2,3-dihydro-;SCHEMBL329946;DTXSID40595324;URZKENDTAFDRKA-UHFFFAOYSA-N;MFCD11223558;AKOS006348023;SB22987;DA-05011;CS-0055007;EN300-120871;J-521544

Suppliers and Price of Isoindolin-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Hydroxyisoindoline
100mg
$ 300.00

Crysdot
Isoindolin-5-ol 95+%
1g
$ 474.00

Crysdot
Isoindolin-5-ol 95+%
5g
$ 1661.00

Chemenu
Isoindolin-5-ol 95%
5g
$ 1565.00

Chemenu
Isoindolin-5-ol 95%
1g
$ 448.00

American Custom Chemicals Corporation
ISOINDOLIN-5-OL 95.00%
5MG
$ 495.01

Alichem
Isoindolin-5-ol
5g
$ 1690.74

Alichem
Isoindolin-5-ol
1g
$ 547.96

AccelPharmtech
2,3-dihydro-1H-Isoindol-5-ol 97.00%
25G
$ 6710.00

AccelPharmtech
2,3-dihydro-1H-Isoindol-5-ol 97.00%
5G
$ 3590.00

Total 13 raw suppliers

Chemical Property of Isoindolin-5-ol

Chemical Property:

PSA：32.26000
LogP:1.32420
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:135.068413911
Heavy Atom Count:10
Complexity:126

Purity/Quality:

97% ^*data from raw suppliers

5-Hydroxyisoindoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(CN1)C=C(C=C2)O
Uses 5-Hydroxyisoindoline is used in organic synthesis, in particular that of 6-Alkoxyisoindolin-1-one based dopamine D2 partial agonists which possess potential antipsychotic properties.

Technology Process of Isoindolin-5-ol

There total 2 articles about Isoindolin-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 127168-88-1
5-methoxy-2,3-dihydro-1H-isoindole

: 54544-67-1
5-hydroxyisoindoline

Guidance literature:: With hydrogen bromide; at 100 ℃; for 2h;
DOI:10.1016/S0960-894X(01)00037-3

Reference yield:

: 50727-06-5
5-hydroxy-isoindole-1,3-dione

: 54544-67-1
5-hydroxyisoindoline

Guidance literature:: 5-hydroxy-isoindole-1,3-dione; With borane; In tetrahydrofuran; at -5 ℃; Inert atmosphere; Reflux;

With hydrogenchloride; water; In tetrahydrofuran; methanol; at 0 ℃; Reflux;

With sodium carbonate; In water;