4-(4-Bromophenyl)-4-methylpentan-2-one

Base Information

Chemical Name:4-(4-Bromophenyl)-4-methylpentan-2-one
CAS No.:54672-48-9
Molecular Formula:C12H15BrO
Molecular Weight:255.155
Hs Code.:
DSSTox Substance ID:DTXSID50498413
Wikidata:Q82348435

Synonyms:4-(4-Bromophenyl)-4-methylpentan-2-one;54672-48-9;DTXSID50498413

Suppliers and Price of 4-(4-Bromophenyl)-4-methylpentan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-(4-Bromophenyl)-4-methylpentan-2-one

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:254.03063
Heavy Atom Count:14
Complexity:202

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)CC(C)(C)C1=CC=C(C=C1)Br

Technology Process of 4-(4-Bromophenyl)-4-methylpentan-2-one

There total 2 articles about 4-(4-Bromophenyl)-4-methylpentan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-86-1,52753-63-6
bromobenzene

: 141-79-7
4-methyl-pent-3-en-2-one

: 54672-48-9
4-(4-bromo-phenyl)-4-methyl-pentan-2-one

Guidance literature:: DOI:10.1021/ja01181a114

Reference yield:

: 54672-48-9
4-(4-bromo-phenyl)-4-methyl-pentan-2-one

Guidance literature:: Brombenzol, Mesityloxid;

Reference yield:

: 54672-48-9
4-(4-bromo-phenyl)-4-methyl-pentan-2-one

: 67437-41-6
1,1-Diphenyl-2-(p-hydroxyphenyl)-3,3-dimethylcyclopropan

Guidance literature:: Multi-step reaction with 9 steps

1: Br₂, aq. NaOH

2: (i) SOCl₂, (ii) /BRN= 1098229/

3: diethyl ether

4: TsOH

5: 1-methyl-pyrrolidin-2-one / 175 °C

6: (rearrangement) / 2-methyl-propan-2-ol / Irradiation

7: (i), (ii) aq. HCl

8: MCPBA / CH₂Cl₂

9: KOH, MeOH / Heating

With 1-methyl-pyrrolidin-2-one; methanol; potassium hydroxide; sodium hydroxide; (Rearrangement); bromine; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In diethyl ether; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ja00481a025