3-ethyl-2-phenyl-1H-indole

Base Information

• Chemical Name: 3-ethyl-2-phenyl-1H-indole
• CAS No.: 53475-25-5
• Molecular Formula: C16H15N
• Molecular Weight: 221.302
• Mol file: 53475-25-5.mol

Synonyms:

Chemical Property of 3-ethyl-2-phenyl-1H-indole

Chemical Property:

• Vapor Pressure: 7.77E-07mmHg at 25°C
• Boiling Point: 418.8°Cat760mmHg
• Flash Point: 186.4°C
• Density: 1.106g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-ethyl-2-phenyl-1H-indole

There total 20 articles about 3-ethyl-2-phenyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C16H15NO2 → 3-ethyl-2-phenyl-1H-indole (53475-25-5)

Guidance literature:

With 3,4,7,8-Tetramethyl-o-phenanthrolin; palladium diacetate; molybdenum hexacarbonyl; In N,N-dimethyl-formamide; at 100 ℃; for 10h; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201500700

Reference yield: 89.0%

phenylhydrazine hydrochloride (59-88-1) + propiophenone (495-40-9) → 3-ethyl-2-phenyl-1H-indole (53475-25-5)

Guidance literature:

With 4-methylbenzenesulfonic acid-based ionic liquid supported on silica gel; In ethanol; at 20 ℃; for 6h;

DOI:10.1007/s10562-016-1721-x

Reference yield: 85.0%

→ 3-ethyl-2-phenyl-1H-indole (53475-25-5)

Guidance literature:

With sodium iodide dihydrate; rhodium contaminated with carbon; sodium carbonate; In N,N-dimethyl-formamide; at 135 ℃; for 36h; Schlenk technique;

upstream raw materials:

butyrophenone phenylhydrazone

3-ethyl-2-phenyl-3H-indol-3-ol

1-phenyl-1-butyne

2-iodophenylamine

Downstream raw materials:

1-(3-ethyl-2-phenyl-1H-indol-1-yl)ethan-1-one

3-ethyl-2-phenylindole-1-carboxaldehyde

3-ethyl-1,2-diphenyl-1H-indole

N-(2,4-Dinitro-phenyl)-N'-[1-(3-ethyl-2-phenyl-indol-1-yl)-meth-(E)-ylidene]-hydrazine