4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-

Base Information

Chemical Name:4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-
CAS No.:118449-23-3
Molecular Formula:C₂₀H₂₁Cl₂N₃OS
Molecular Weight:422.378
Hs Code.:
DSSTox Substance ID:DTXSID90152128
Wikidata:Q83018728

Synonyms:4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-;7-Chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-4(3H)-quinazolinone;118449-23-3;C20H21Cl2N3OS;DTXSID90152128;C20-H21-Cl2-N3-O-S;LS-140457

Suppliers and Price of 4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-

Chemical Property:

Vapor Pressure:8.07E-13mmHg at 25°C
Boiling Point:565.7°C at 760 mmHg
PKA:9.30±0.28(Predicted)
Flash Point:296°C
PSA：63.43000
Density:1.3g/cm³
LogP:5.04470
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:421.0782389
Heavy Atom Count:27
Complexity:559

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC=C1Cl)N2C(=O)C3=C(C=C(C=C3)Cl)N=C2SCCCN(C)C

Technology Process of 4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)-

There total 3 articles about 4(3H)-Quinazolinone, 7-chloro-3-(3-chloro-2-methylphenyl)-2-((3-(dimethylamino)propyl)thio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 109-54-6
3-(Dimethylamino)propyl chloride

: 118449-39-1
7-Chloro-3-(3-chloro-2-methyl-phenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one

: 118449-23-3
7-Chloro-3-(3-chloro-2-methyl-phenyl)-2-(3-dimethylamino-propylsulfanyl)-3H-quinazolin-4-one

Guidance literature:: With sodium hydroxide; In ethanol; Ambient temperature;

Reference yield:

: 19241-35-1
1-chloro-3-isothiocyanato-2-methylbenzene

: 118449-23-3
7-Chloro-3-(3-chloro-2-methyl-phenyl)-2-(3-dimethylamino-propylsulfanyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ethanol / Heating

2: 70 percent / sodium hydroxide / ethanol / Ambient temperature

With sodium hydroxide; In ethanol;

Reference yield:

: 89-77-0
2-Amino-4-chlorobenzoic acid

: 118449-23-3
7-Chloro-3-(3-chloro-2-methyl-phenyl)-2-(3-dimethylamino-propylsulfanyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ethanol / Heating

2: 70 percent / sodium hydroxide / ethanol / Ambient temperature

With sodium hydroxide; In ethanol;