Pyrazinecarboxylic acid, 5,6-bis(4-methylphenyl)-

Base Information

• Chemical Name: Pyrazinecarboxylic acid, 5,6-bis(4-methylphenyl)-
• CAS No.: 548760-12-9
• Molecular Formula: C19H16N2O2
• Molecular Weight: 304.348
• Mol file: 548760-12-9.mol

Synonyms:

Chemical Property of Pyrazinecarboxylic acid, 5,6-bis(4-methylphenyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pyrazinecarboxylic acid, 5,6-bis(4-methylphenyl)-

There total 2 articles about Pyrazinecarboxylic acid, 5,6-bis(4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H18N2O2 (845728-82-7) → 5,6-di-p-tolyl-pyrazine-2-carboxylic acid (548760-12-9)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2007.04.087

Reference yield:

C19H18N2O2 → 5,6-di-p-tolyl-pyrazine-2-carboxylic acid (548760-12-9)

Guidance literature:

With air; In methanol; for 7h;

DOI:10.1016/j.bmc.2007.03.075

Reference yield: 29.0%

5,6-di-p-tolyl-pyrazine-2-carboxylic acid (548760-12-9) + aniline (62-53-3) → C25H21N3O

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; at 25 ℃; for 20h;

DOI:10.1016/j.bmc.2007.03.075

upstream raw materials:

C₂₀H₁₈N₂O₂

Downstream raw materials:

C₁₉H₁₅ClN₂O