5-Pyridoxolactone

Base Information

Chemical Name:5-Pyridoxolactone
CAS No.:4543-56-0
Molecular Formula:C8H7NO3
Molecular Weight:165.148
Hs Code.:2934999090
European Community (EC) Number:809-321-8
NSC Number:41813,15983
UNII:UA6Q3JV3FZ
DSSTox Substance ID:DTXSID80196511
Nikkaji Number:J101.560E
Wikidata:Q27105557
Metabolomics Workbench ID:38509
Mol file:4543-56-0.mol

Synonyms:5-pyridoxic acid lactone;5-pyridoxolactone

Suppliers and Price of 5-Pyridoxolactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Pyridoxolactone
100mg
$ 1570.00

Sigma-Aldrich
5-Pyridoxolactone ≥98.5% (HPLC and enzymatic)
50mg
$ 484.00

Sigma-Aldrich
5-Pyridoxolactone ≥98.5% (HPLC and enzymatic)
10mg
$ 115.00

American Custom Chemicals Corporation
7-HYDROXY-6-METHYL-FURO[3,4-C]PYRIDIN-3(1H)-ONE 95.00%
5MG
$ 505.46

AccelPharmtech
7-hydroxy-6-methyl-Furo[3,4-c]pyridin-3(1H)-one 97.00%
25G
$ 13300.00

AccelPharmtech
7-hydroxy-6-methyl-Furo[3,4-c]pyridin-3(1H)-one 97.00%
5G
$ 5360.00

AccelPharmtech
7-hydroxy-6-methyl-Furo[3,4-c]pyridin-3(1H)-one 97.00%
1G
$ 3120.00

Total 6 raw suppliers

Chemical Property of 5-Pyridoxolactone

Chemical Property:

Vapor Pressure:4.52E-11mmHg at 25°C
Boiling Point:511.2°Cat760mmHg
Flash Point:263°C
PSA：59.42000
Density:1.448g/cm³
LogP:0.76600
Storage Temp.:?20°C
Solubility.:Methanol
XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:165.042593085
Heavy Atom Count:12
Complexity:207

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Pyridoxolactone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C2C(=C1O)COC2=O
Uses 5-Pyridoxolactone is an intermediate in the synthesis of analogues of Pyridoxine (P991735), one of the vitamins of the B6 complex; present in many foodstuffs (yeast, liver and cereals). Pyridoxine has a role in transporting protein Bsu1, Pyridoxine contributes to thiamine uptake; characterization of thiamine (vitamin B1) transporter Thi9 from Schizosaccharomyces pombe.

Technology Process of 5-Pyridoxolactone

There total 25 articles about 5-Pyridoxolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1198620-33-5
N,3-bis(benzyloxy)-4-(hydroxymethyl)-N-(4-methoxybenzyl)pyridine-2,5-dicarboxamide

: 4543-56-0
7-hydroxy-6-methyl-1H-furo[3,4-c]pyridin-3-one

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethyl acetate;

Reference yield:

: 2397-71-9
5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester

: 65-23-6
5-hydroxy-6-methyl-3,4-pyridinedimethanol

: 4543-56-0
7-hydroxy-6-methyl-1H-furo[3,4-c]pyridin-3-one

: 809272-94-4
ethyl 5-hydroxy-4-(hydroxymethyl)-6-methylnicotinate

Guidance literature:: With Me₃SiH(OEt)2; tetrabutyl ammonium fluoride; In tetrahydrofuran; at 22 ℃; for 24h;
DOI:10.3390/81200873

Reference yield:

: 1136-52-3
(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

: 4543-56-0
7-hydroxy-6-methyl-1H-furo[3,4-c]pyridin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KMnO₄

2: aq. AcOH

With potassium permanganate; acetic acid;
DOI:10.1021/jo01026a013