2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide

Base Information

Chemical Name:2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide
CAS No.:55149-75-2
Molecular Formula:C11H9N3O3S
Molecular Weight:263.277
Hs Code.:
DSSTox Substance ID:DTXSID20707680

Synonyms:55149-75-2;SCHEMBL11549126;DTXSID20707680;IJRIPLJETWNBDY-UHFFFAOYSA-N;2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide;alpha-cyano-beta-(2-nitro-5-methylthiophenyl)acrylamide

Suppliers and Price of 2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:263.03646233
Heavy Atom Count:18
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=CC(=C(C=C1)[N+](=O)[O-])C=C(C#N)C(=O)N

Technology Process of 2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide

There total 3 articles about 2-Cyano-3-[5-(methylsulfanyl)-2-nitrophenyl]prop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 55149-72-9
α-cyano-β-(2-nitro-5-chlorophenyl)acrylamide

: 5188-07-8
sodium thiomethoxide

: 55149-75-2
(E)-2-Cyano-3-(5-methylsulfanyl-2-nitro-phenyl)-acrylamide

Guidance literature:: In N,N-dimethyl-formamide; 1.) 0 deg C, 1 h, 2.) 2 h;
DOI:10.1021/jm00177a010

Reference yield:

: 6628-86-0
5-chloro-2-nitrobenzaldehyde

: 55149-75-2
(E)-2-Cyano-3-(5-methylsulfanyl-2-nitro-phenyl)-acrylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / piperidine / methanol / 2 h / Heating

2: 88 percent / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 2 h

With piperidine; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00177a010