tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate
CAS No.:556824-87-4
Molecular Formula:C16H24N2O2
Molecular Weight:276.379
Hs Code.:
Mol file:556824-87-4.mol

Synonyms:3-amino-2-phenyl-1-tertiary butoxycarbonylpiperidine;(2R3R,2S3S)-1-(tert-butoxycarbonyl)-2-phenylpiperidin-3-amine;1-tert-butoxycarbonyl-(2S,3S)-3-amino-2-phenylpiperidine;

Suppliers and Price of tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate

Chemical Property:

PSA：55.56000
LogP:3.72410

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate

There total 1 articles about tert-butyl 3-aMino-2-phenylpiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.8%

: 24424-99-5
di-tert-butyl dicarbonate

: 58373-46-9,160551-72-4
(2R₃R,2S₃S)-cis-2-phenylpiperidin-3-amine

: (+/-)-(2R₃R,2S₃S)-l-(tert-butoxycarbonyl)-2-phenylpiperidin-3-amine

: 556824-87-4
(+/-)-(2R₃R,2S₃S)-1-(tert-Butoxycarbonyl)-2-phenylpiperidin-3-amine

Guidance literature:: With sodium hydroxide; In ethanol; water; at 10 - 15 ℃; for 3h; pH=11.8 - 12.2;

Reference yield: 20.0%

: 556824-87-4
(+/-)-(2R₃R,2S₃S)-1-(tert-Butoxycarbonyl)-2-phenylpiperidin-3-amine

: 208831-21-4
2-(cyclopropoxy)-5-(trifluoromethoxy)benzaldehyde

: (+/-)-(2R₃R,2S₃S)-N-{[2-Cyclopropoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine Dihydrochloride

Guidance literature:: With sodium borohydrid; trifluoroacetic acid; citric acid; silica gel; In methanol; ethereal hydrogen chloride; ethanol; dichloromethane; ethyl acetate;

Reference yield: 20.0%

: 556824-87-4
(+/-)-(2R₃R,2S₃S)-1-(tert-Butoxycarbonyl)-2-phenylpiperidin-3-amine

? molecular sieves: ? molecular sieves

: 208831-21-4
2-(cyclopropoxy)-5-(trifluoromethoxy)benzaldehyde

: (+/-)-(2R₃R,2S₃S)-N-{[2-Cyclopropoxy-5-(trifluoromethoxy)phenyl]methyl}-2-phenylpiperidin-3-amine Dihydrochloride

Guidance literature:: With sodium borohydrid; trifluoroacetic acid; citric acid; In methanol; ethereal hydrogen chloride; ethanol; dichloromethane; ethyl acetate;