2-(1-Benzothiophen-2-yl)-5-bromopyridine

Base Information

Chemical Name:2-(1-Benzothiophen-2-yl)-5-bromopyridine
CAS No.:557793-46-1
Molecular Formula:C13H8BrNS
Molecular Weight:290.17800
Hs Code.:
DSSTox Substance ID:DTXSID20587848
Nikkaji Number:J2.064.435D
Wikidata:Q82480335
Mol file:557793-46-1.mol

Synonyms:557793-46-1;2-(1-Benzothiophen-2-yl)-5-bromopyridine;2-(2-BENZO[B]THIENYL)-5-BROMOPYRIDINE;SCHEMBL4014804;DTXSID20587848;2-Benzo[b]thien-2-yl-5-bromopyridine;DB-182063;2-(Benzo[b]thiophen-2-yl)-5-bromopyridine

Suppliers and Price of 2-(1-Benzothiophen-2-yl)-5-bromopyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-(1-Benzothiophen-2-yl)-5-bromopyridine

Chemical Property:

PSA：41.13000
LogP:4.72580
XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:288.95608
Heavy Atom Count:16
Complexity:248

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(S2)C3=NC=C(C=C3)Br

Technology Process of 2-(1-Benzothiophen-2-yl)-5-bromopyridine

There total 5 articles about 2-(1-Benzothiophen-2-yl)-5-bromopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 624-28-2
2,5-dibromopyridine

: 98437-23-1
benzo[b]thiophene-2-boronic acid

: 557793-46-1
2-(benzo[b]thiophen-2-yl)-5-bromopyridine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; toluene; at 100 ℃; for 20h;
DOI:10.1039/b400160e

Reference yield: 81.0%

: 98437-23-1
benzo[b]thiophene-2-boronic acid

: 223463-13-6
2-iodo-5-bromopyridine

: 557793-46-1
2-(benzo[b]thiophen-2-yl)-5-bromopyridine

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; at 80 ℃; for 24h;
DOI:10.1021/jo070968e

Reference yield: 60.0%

: 624-28-2
2,5-dibromopyridine

: 376584-76-8
2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophene

: 557793-46-1
2-(benzo[b]thiophen-2-yl)-5-bromopyridine

Guidance literature:: 2,5-dibromopyridine; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; at 75 ℃;

2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]thiophene; In tetrahydrofuran; at 20 ℃; for 16h;
DOI:10.1021/ja039445o