Morpholine, 4-[1-(4-chlorophenyl)ethenyl]-

Base Information

• Chemical Name: Morpholine, 4-[1-(4-chlorophenyl)ethenyl]-
• CAS No.: 55949-66-1
• Molecular Formula: C12H14ClNO
• Molecular Weight: 223.702
• DSSTox Substance ID: DTXSID20448460
• Nikkaji Number: J1.016.784A
• Wikidata: Q82267452
• Mol file: 55949-66-1.mol

Synonyms:Morpholine, 4-[1-(4-chlorophenyl)ethenyl]-;55949-66-1;DTXSID20448460;1-Morpholino-1-(4-chlorophenyl)ethene

Chemical Property of Morpholine, 4-[1-(4-chlorophenyl)ethenyl]-

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 223.0763918
• Heavy Atom Count: 15
• Complexity: 218

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=C(C1=CC=C(C=C1)Cl)N2CCOCC2

Technology Process of Morpholine, 4-[1-(4-chlorophenyl)ethenyl]-

There total 2 articles about Morpholine, 4-[1-(4-chlorophenyl)ethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

morpholine (110-91-8,99108-56-2) + para-chloroacetophenone (99-91-2) → 4-[1-(4-chloro-phenyl)-vinyl]-morpholine (55949-66-1)

Guidance literature:

With sulfuric acid; silica gel; for 0.916667h; Heating;

Reference yield:

→ 4-[1-(4-chloro-phenyl)-vinyl]-morpholine (55949-66-1)

Guidance literature:

Reference yield: 99.0%

4-[1-(4-chloro-phenyl)-vinyl]-morpholine (55949-66-1) → N-(4-chlorobenzoyl)morpholine (19202-04-1)

Guidance literature:

With tris(2 2'-bipyridyl)ruthenium(II) chloride hexahydrate; oxygen; caesium carbonate; In acetonitrile; at 20 ℃; for 16h; Irradiation; Inert atmosphere;

DOI:10.1055/s-0034-1378205

upstream raw materials:

morpholine

para-chloroacetophenone

Downstream raw materials:

4-[1-(4-Chloro-phenyl)-1-(4,5-dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yl)-ethyl]-morpholine

4-[1-(4-Chloro-phenyl)-1-(2-oxo-2λ⁵-benzo[1,3,2]dioxaphosphol-2-yl)-ethyl]-morpholine

ethyl 4-(4-chlorophenyl)-4-oxobutanoate

[1-(4-Chloro-phenyl)-1-morpholin-4-yl-ethyl]-phosphonic acid mono-(2-hydroxy-phenyl) ester