Norstictic acid

Base Information

• Chemical Name: Norstictic acid
• CAS No.: 571-67-5
• Molecular Formula: C₁₈H₁₂O₉
• Molecular Weight: 372.288
• UNII: D377V822FG
• DSSTox Substance ID: DTXSID30972564
• Nikkaji Number: J53.078F
• Wikipedia: Norstictic_acid
• Wikidata: Q3604544
• Pharos Ligand ID: CD7Y5VKYWM28
• Metabolomics Workbench ID: 127819
• ChEMBL ID: CHEMBL228281
• Mol file: 571-67-5.mol

Synonyms:norstictic acid

Chemical Property of Norstictic acid

Chemical Property:

• Vapor Pressure: 1.49E-24mmHg at 25°C
• Boiling Point: 764.2°Cat760mmHg
• Flash Point: 283.7°C
• PSA: 139.59000
• Density: 1.714g/cm³
• LogP: 2.01330
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 1
• Exact Mass: 372.04813196
• Heavy Atom Count: 27
• Complexity: 651

Purity/Quality:

99% ^*data from raw suppliers

Norstictic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C2=C1C(=O)OC3=C(O2)C4=C(C(=C3C)O)C(=O)OC4O)C=O)O
• Description: Norstictic acid is a lichen metabolite that has been found in R. farinacea and has antimicrobial and anticancer activities. It is active against A. hydrophilia, B. subtilis, L. monocytogenes, P. vulgaris, S. faecalis, C. albicans, and C. glabrata (MICs = 0.1-6.7 mM). Norstictic acid (1-100 μM) inhibits proliferation, migration, and invasion of MDA-MB-231 cells. In vivo, norstictic acid (15 mg/kg, i.p.) reduces tumor growth in an MDA-MB-231/GFP mouse xenograft model.