4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine

Base Information

Chemical Name:4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine
CAS No.:562086-30-0
Molecular Formula:C14H14N2O2
Molecular Weight:242.277
Hs Code.:2933399090
Mol file:562086-30-0.mol

Synonyms:4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine;4-carbomethoxy-6,6'-dimethyl-2,2'-bipyridine;methyl 6,6'-dimethyl-[2,2'-bipyridine]-4-carboxylate;[2,2'-Bipyridine]-4-carboxylic acid,6,6'-dimethyl-,methyl ester;

Suppliers and Price of 4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl6,6'-dimethyl-[2,2'-bipyridine]-4-carboxylate 95+%
5g
$ 852.00

Chemenu
methyl6,6''-dimethyl-[2,2''-bipyridine]-4-carboxylate 95%
5g
$ 804.00

Alichem
Methyl6,6'-dimethyl-[2,2'-bipyridine]-4-carboxylate
5g
$ 959.30

Total 15 raw suppliers

Chemical Property of 4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine

Chemical Property:

PSA：52.08000
LogP:2.54700

Purity/Quality:

97% ^*data from raw suppliers

Methyl6,6'-dimethyl-[2,2'-bipyridine]-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine

There total 2 articles about 4-methoxycarbonyl-6,6'-dimethyl-2,2'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5315-25-3
2-bromo-6-methylpyridine

: 562086-28-6
methyl 2-methyl-6-<(p-toluenesulfonyl)oxy>pyridine-4-carboxylate

: 4411-80-7
6,6'-dimethyl-2,2'-bipyridine

: 562086-30-0
6,6′-dimethyl-2,2′-bipyridine-4-carboxylic acid methyl ester

Guidance literature:: 2-bromo-6-methylpyridine; With n-butyllithium; tributyltin chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;

methyl 2-methyl-6-<(p-toluenesulfonyl)oxy>pyridine-4-carboxylate; With triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In xylene; for 24h; Heating;
DOI:10.1081/SCC-120015770

Reference yield:

: 5315-25-3
2-bromo-6-methylpyridine

: 4-carbomethoxy-6-methyl-2-(methanesulfonyloxy)pyridine

: 4411-80-7
6,6'-dimethyl-2,2'-bipyridine

: 562086-30-0
6,6′-dimethyl-2,2′-bipyridine-4-carboxylic acid methyl ester

Guidance literature:: 2-bromo-6-methylpyridine; With n-butyllithium; tributyltin chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃;

4-carbomethoxy-6-methyl-2-(methanesulfonyloxy)pyridine; With triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; In xylene; for 24h; Heating;
DOI:10.1081/SCC-120015770

Reference yield:

: 562086-30-0
6,6′-dimethyl-2,2′-bipyridine-4-carboxylic acid methyl ester

: 928306-83-6
4-(tert-butyldiphenylsilanyloxymethyl)-6,6'-dimethyl-2,2'-bipyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / NaBH₄ / methanol

2: 94 percent / imidazole / dimethylformamide / 48 h / 20 °C

With 1H-imidazole; sodium tetrahydroborate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2006.12.012