1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)-

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Chemical Name:1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)-
CAS No.:565229-25-6
Molecular Formula:C28H44O7
Molecular Weight:492.653
Hs Code.:

1,3-Dioxane,
2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R
)-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl]
-2-pentenyl]-, (4S,5S)-

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Suppliers and Price of 1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)-

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Technology Process of 1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)-

There total 18 articles about 1,3-Dioxane, 2-(4-methoxyphenyl)-5-methyl-4-[(1S,2Z)-1-methyl-5-[(2S,3R,4S,5R,6R )-tetrahydro-6-methoxy-4-(methoxymethoxy)-3,5-dimethyl-2H-pyran-2-yl] -2-pentenyl]-, (4S,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: C₃₃H₃₅O₃P

: 565228-65-1
(2S,3R,4S,5R,6R)-3-(6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl)propionaldehyde

: 565229-25-6
(4R,5S)-4-{(1S,2Z)-5-[(2S,3S,4S,5R,6R)-6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl]-1-methylpent-2-enyl}-2-(4-methoxyphenyl)-5-methyl[1,3]dioxane

Guidance literature:: In tetrahydrofuran; at -78 - 20 ℃; for 4.33333h;

Reference yield: 67.0%

: (2S)-{2-[(4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]propyl}triphenylphosphane iodide

: 565229-78-9
(2S,3S,4S,5R,6R)-3-(6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl)propionaldehyde

: 565229-25-6
(4R,5S)-4-{(1S,2Z)-5-[(2S,3S,4S,5R,6R)-6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl]-1-methylpent-2-enyl}-2-(4-methoxyphenyl)-5-methyl[1,3]dioxane

Guidance literature:: (2S)-{2-[(4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]propyl}triphenylphosphane iodide; With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 0.333333h;

(2S,3S,4S,5R,6R)-3-(6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl)propionaldehyde; In tetrahydrofuran; at -78 - 20 ℃; for 4.33333h;
DOI:10.1021/jm0204136

Reference yield:

: 565229-01-8
(2R,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-6-(4-methoxy-benzyloxy)-2-methyl-hexanal

: 565229-25-6
(4R,5S)-4-{(1S,2Z)-5-[(2S,3S,4S,5R,6R)-6-methoxy-4-methoxymethoxy-3,5-dimethyltetrahydropyran-2-yl]-1-methylpent-2-enyl}-2-(4-methoxyphenyl)-5-methyl[1,3]dioxane

Guidance literature:: Multi-step reaction with 8 steps

1.1: Bu₂BOTf; N,N-diisopropylethylamine / CH₂Cl₂ / 0.5 h / 0 °C

1.2: CH₂Cl₂ / 2.17 h / -78 - 0 °C

1.3: 2.29 g / aq. H₂O₂; phosphate buffer / CH₂Cl₂; methanol / 1 h / pH 7.0

2.1: 92 percent / N,N-diisopropylethylamine / CH₂Cl₂ / Heating

3.1: 83 percent / HF*pyridine; pyridine / methanol / 48 h / 20 °C

4.1: diisobutylaluminum hydride / tetrahydrofuran; CH₂Cl₂ / 1 h / -78 °C

5.1: pyridinium p-toluenesulfonate / 15 h / 20 °C

6.1: H₂ / Pd/C / ethyl acetate / 3 h / 20 °C / atmospheric pressure

7.1: 274 mg / Dess-Martin periodinane / CH₂Cl₂ / 20 °C

8.1: NaHMDS / tetrahydrofuran / 0.33 h / 20 °C

8.2: 67 percent / tetrahydrofuran / 4.33 h / -78 - 20 °C

With pyridine; di-n-butylboryl trifluoromethanesulfonate; hydrogen; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; Dess-Martin periodane; pyridine hydrogenfluoride; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate; 7.1: Dess-Martin oxidation / 8.2: Wittig olefination;
DOI:10.1021/jm0204136